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Merck
모든 사진(3)

문서

N7632

Sigma-Aldrich

N-Nitrosodiethanolamine

동의어(들):

2,2′-(Nitrosoimino)bisethanol, N,N-Diethanolnitrosamine, Bis(2-hydroxyethyl)nitrosamine, NDELA

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About This Item

실험식(Hill 표기법):
C4H10N2O3
CAS Number:
Molecular Weight:
134.13
Beilstein:
1762620
MDL number:
UNSPSC 코드:
12352116
PubChem Substance ID:
NACRES:
NA.25

형태

liquid

불순물

≤10% Isopropanol

저장 온도

2-8°C

SMILES string

OCCN(N=O)CCO

InChI

1S/C4H10N2O3/c7-3-1-6(5-9)2-4-8/h7-8H,1-4H2

InChI key

YFCDLVPYFMHRQZ-UHFFFAOYSA-N

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애플리케이션


  • Changes in levels of N-nitrosamine formed from amine-containing compounds during chloramination via photocatalytic pretreatment with immobilized TiO(2): Effect of source water and pH.: In this study, NDELA is used as a standard to examine how the formation of nitrosamines, such as N-Nitrosodiethanolamine, is affected by different water sources and pH levels during water treatment processes (Seid et al., 2022).

  • Monitoring and risk assessment of hazardous chemicals in toy-slime and putty in the Netherlands.: This research focuses on the presence of N-Nitrosodiethanolamine in children′s toys, providing important data for consumer safety and regulatory standards (Braver et al., 2021).

  • On-line solid phase extraction-ultra-high performance liquid chromatography coupled to tandem mass spectrometry for the determination of N-nitrosodiethanolamine in baby shampoo.: Highlights the usage of N-Nitrosodiethanolamine as an analytical standard in application of advanced chromatographic techniques for detecting harmful substances in consumer products, ensuring product safety and regulatory compliance (Tada et al., 2021).

픽토그램

FlameHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Carc. 1B - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point (°F)

52.9 °F

Flash Point (°C)

11.6 °C

개인 보호 장비

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Michelle K Dennehy et al.
Chemical research in toxicology, 18(3), 556-565 (2005-03-22)
N-Nitrosodiethanolamine (NDELA) is a bident carcinogen that undergoes both P-450 mediated alpha-hydroxylation and beta-oxidation, leading ultimately to the formation of two prominent DNA adducts, glyoxaldeoxyguanosine (gdG) and O6-2-hydroxyethyldeoxyguanosine (OHEdG), in rat liver. HPLC coupled with electrospray ionization (ESI) and tandem
M Futakuchi et al.
Cancer letters, 106(2), 263-269 (1996-09-10)
Potential synergism between four N-nitroso compounds (nitrosomorpholine, nitrosodimethylamine, nitrosodiethanolamine, nitroso-oxazolidine) in rat liver carcinogenesis was examined in the medium-term bioassay. Male F344 rats were initially given diethylnitrosamine (DEN, 200 mg/kg, ip) and beginning 2 weeks later received test chemicals for
R C Schothorst et al.
Analytical and bioanalytical chemistry, 381(3), 681-685 (2005-01-26)
We have developed and validated in-house a liquid chromatography and mass spectrometry (LC-MS-MS) method for determination of N-nitrosodiethanolamine (NDELA) in cosmetics. The sample is diluted with water and then a C18 clean-up is performed. The average recovery of NDELA is
Richard N Loeppky et al.
Chemical research in toxicology, 15(4), 470-482 (2002-04-16)
The mechanism by which environmentally prevalent N-nitrosodiethanolamine (NDELA) and related 2-hydroxyethyl- or other beta-oxidized nitrosamines initiate the carcinogenic process has remained obscure. (32)P-Postlabeling assays for the pH sensitive glyoxal-deoxyguanosine (gdG) and the O(6)-2-hydroxyethyldeoxyguanosine (OHEdG) DNA adducts have been developed as
R Hasegawa et al.
Cancer letters, 123(2), 185-191 (1998-03-07)
Complete carcinogens must possess both initiating and promoting properties. Most N-nitroso compounds are mutagens and are considered to be initiators, but some are not mutagenic and yet are complete carcinogens. To investigate the two activities, brief treatments of male F344

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