N6909

Neurturin human

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• 동의어(들): NRTN, NTN
• MDL number: MFCD01867712
• UNSPSC 코드: 51111800

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: >95% (SDS-PAGE)
• 형태: lyophilized powder
• 효능: 15-50 ng/mL ED₅₀
• 분자량: monomer calculated mol wt ~12.5 kDa; predicted mol wt ~14 kDa by SDS-PAGE (reducing)
• 저장 조건: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• 불순물: endotoxin, tested
• UniProt 수납 번호: Q99748
• 저장 온도: −20°C
• 유전자 정보: human ... NRTN(4902)

설명

생화학적/생리학적 작용

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways. Human and mouse NTN share 91% sequence identity.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin.

분석 메모

The biological activity is measured by its ability to bind recombinant human GFRα2/Fc.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)