N214

Neutrophil Activating Peptide-2 human

>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

• 동의어(들): NAP-2
• MDL number: MFCD00241917
• UNSPSC 코드: 51111800

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 분석: >97% (SDS-PAGE)
• 양식: lyophilized powder
• 효능: 0.1-0.3 μg/mL ED₅₀ (cytochalasin B treated human neutrophils); 0.1-0.5 ng/mL ED₅₀ (BaF/3 hCXCR-2 transfected cells)
• 분자량: ~7.6 kDa
• 저장 조건: avoid repeated freeze/thaw cycles (Storage in "frost-free" freezers is not recommended)
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• UniProt 수납 번호: P02775
• 저장 온도: −20°C
• 유전자 정보: human ... PPBP(5473)

설명

생화학적/생리학적 작용

Neutrophil Activating Peptide-2, a member of the CXC chemokine family, chemoattracts and activates neutrophils and also binds CXCR-2. NAP-2 is proteolytically processed C-terminal fragments of platelet basic protein (PBP), which is found in the α-granules of human platelets.

물리적 형태

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.

분석 메모

The biological activity is measured by the induction of myeloperoxidase release from cytochalasin B treated human neutrophils.