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Merck
모든 사진(1)

문서

MAK547

Sigma-Aldrich

High Sensitivity Beta-Hydroxybutyrate (Ketone Body) Assay Kit

sufficient for 200 fluorometric tests

동의어(들):

High Sensitivity Beta-Hydroxybutyrate Assay Kit

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About This Item

UNSPSC 코드:
41116104
NACRES:
NA.21

응용 분야

cosmetics
food and beverages

검출 방법

fluorometric

관련 질환(들)

endocrinological disorders, diabetes; gastrointestinal diseases

배송 상태

dry ice

저장 온도

−20°C

일반 설명

Ketone bodies are produced by the liver and used peripherally as an energy source when blood glucose levels drop. The two main ketone bodies are beta-hydroxybutyrate (β-HB) and acetoacetate, while acetone is the third abundant ketone body. Normally these two predominant ketone bodies are present in small amounts in the blood during fasting and prolonged exercise. In patients who have diabetes, alcohol or salicylate poisoning, hormone deficiency, childhood hypoglycemia and other acute disease states, large quantities of ketone bodies are found in the blood. The over-production and accumulation of ketone bodies in the blood (ketosis) can lead to pathological metabolic acidosis (ketoacidosis). Blood ketone testing methods that quantify β-HB, the predominant ketone body in the blood (approximately 75%) have been used for diagnosing and monitoring treatment of ketoacidosis.

​The Beta-Hydroxybutyrate Assay Kit offers a sensitive fluorescent assay for measuring Beta-HB levels in biological samples. This assay is based on an enzyme coupled reaction of β-HB, in which the product NADH can be specifically monitored by a fluorescent NADH sensor. The detection limit of this assay kit is 1.4 µM β-HB in a 100 µL reaction volume.

픽토그램

Health hazardCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3


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