추천 제품
![1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one powder](/deepweb/assets/sigmaaldrich/product/structures/764/715/605dc5a5-0864-471b-a71e-bd2aa6553c1d/640/605dc5a5-0864-471b-a71e-bd2aa6553c1d.png)
분석
>98% (HPLC)
형태
powder
저장 온도
2-8°C
SMILES string
Cl[H].Cl[H].CNCCNS(=O)(=O)c1cccc2cnccc12
InChI
1S/C12H15N3O2S.2ClH/c1-13-7-8-15-18(16,17)12-4-2-3-10-9-14-6-5-11(10)12;;/h2-6,9,13,15H,7-8H2,1H3;2*1H
InChI key
RJJLZYZEVNCZIW-UHFFFAOYSA-N
유전자 정보
human ... CALCRL(10203) , PRKAR1A(5573) , PRKAR1AP(5574) , PRKAR1B(5575) , PRKAR2A(5576) , PRKAR2B(5577)
rat ... Calcrl(25029)
생화학적/생리학적 작용
cAMP and cGMP-dependent protein kinase inhibitor.
특징 및 장점
This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Guijin Ma et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 131, 110766-110766 (2020-11-07)
Chrysin, a natural flavonoid available in honey, propolis and medicinal plants, has been shown to be vasorelaxant in some vascular beds. Proper intake of an alimental vasodilator as a food additive may be a promising strategy for prevention and treatment
F Shirakawa et al.
Molecular and cellular biology, 9(6), 2424-2430 (1989-06-01)
We have examined whether a precursor form of NF-kappa B, a DNA-binding protein that plays a role in the transcriptional control of several genes, including kappa immunoglobulin light chain and interleukin-2 receptor alpha subunit, could be activated in vitro by
H Hidaka et al.
Biochemistry, 23(21), 5036-5041 (1984-10-09)
Naphthalenesulfonamides such as N-(6-amino-hexyl)-5-chloro-1-naphthalenesulfonamide (W-7) are potent calmodulin (CaM) antagonists and act upon several protein kinases at higher concentration. When the naphthalene ring was replaced by isoquinoline, the derivatives were no longer CaM antagonists but retained the ability to inhibit
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