M6684

Anti-Matrix Metalloproteinase-24, Hinge Region antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

• 동의어(들): Anti-MMP-24, Anti-MT5-MMP
• MDL number: MFCD03097031
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 200
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous glycerol solution
• 분자량: antigen 65 kDa
• 종 반응성: human, mouse
• 농도: ~1 mg/mL
• 기술: flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; indirect ELISA: suitable; western blot: 1:2,000
• UniProt 수납 번호: Q9Y5R2
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... MMP24(10893) ; mouse ... Mmp24(17391)

설명

일반 설명

Matrix metalloproteinase-24 (MMP-24) is expressed majorly in the nervous system and also in the lungs, kidneys and liver. It is a 64kDa protein whose gene is localized on human chromosome 20.

특이성

Reacts with reduced and native MMP-24. Recognizes the pro-form of MMP-24 as well as activation/breakdown products.

면역원

synthetic peptide corresponding to the hinge region of mouse matrix metalloproteinase-24 (membrane-type matrix metalloproteinase-5).

생화학적/생리학적 작용

Matrix metalloproteinase-24 (MMP-24) is involved in the conversion of pro-matrix metalloproteinase-2 to its functional active form. It may be important for brain development and studies have shown that it is overexpressed in gastric cancer.

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 50% glycerol and 15 mM sodium azide.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable