M5273

Monensin sodium salt

90-95% (TLC)

• 동의어(들): Monensin A sodium salt
• 실험식(Hill 표기법): C₃₆H₆₁NaO₁₁
• CAS Number: 22373-78-0
• Molecular Weight: 692.85
• Beilstein: 4122200
• EC Number: 244-941-7
• MDL number: MFCD00077826
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24896992
• NACRES: NA.77

속성

• 분석: 90-95% (TLC)
• 항생제 활성 스펙트럼: Gram-negative bacteria; Gram-positive bacteria; fungi; parasites; viruses
• 동작 모드: cell membrane | interferes
• 저장 온도: 2-8°C
• SMILES string: [H][C@]1([C@@]2(CC)O[C@]([C@@]3(C)OC4(C[C@H](O)[C@@H](C)[C@@]([H])([C@@H](C)[C@@H](OC)[C@@H](C([O-])=O)C)O4)CC3)([H])CC2)[C@@H](C)C[C@]([H])([C@@]5([H])O[C@@](O)(CO)[C@H](C)C[C@@H]5C)O1.[Na+]
• InChI: 1S/C36H62O11.Na/c1-10-34(31-20(3)16-26(43-31)28-19(2)15-21(4)36(41,18-37)46-28)12-11-27(44-34)33(8)13-14-35(47-33)17-25(38)22(5)30(45-35)23(6)29(42-9)24(7)32(39)40;/h19-31,37-38,41H,10-18H2,1-9H3,(H,39,40);/q;+1/p-1/t19-,20-,21+,22+,23-,24-,25-,26+,27+,28-,29+,30-,31+,33-,34-,35?,36-;/m0./s1
• InChI key: XOIQMTLWECTKJL-BEMBKCOJSA-M

설명

일반 설명

Chemical structure: polyether

Monensin is a polyether ionophoric antibiotic, which is produced by Streptomyces cinnamonensis. It is used to treat bacterial, fungal and parasitic infections. Monensin prevents the growth of colon cancer cells. It facilitates the transport of sodium and potassium ions between intracellular and extracellular spaces. Monensin prevents coccidiosis in poultry production.

애플리케이션

Monensin sodium salt has been used:

• for the intracellular staining of cytokines
• to study its effects on the regulation of nuclear factor-κ B (NF-κB ) activation
• as a positive control to study its effects on in vitro rumen fermentation

생화학적/생리학적 작용

Na⁺ ionophore; blocks glycoprotein secretion; may induce catecholamine secretion from chromaffin cells. Useful in potentiometric and spectroscopic studies of alkali metal ion complexes.

제조 메모

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 6 months at 4°C.

안전성 정보

• 픽토그램: GHS06,GHS08,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H300,H319,H373,H411
• 예방조치 성명서: P260 - P264 - P273 - P301 + P310 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 2 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - STOT RE 2
• 표적 기관: Heart,muscle
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges