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주요 문서

COO/COA

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L8250

DL-Leucinamide hydrochloride

Name: <SC>DL</SC>-Leucinamide hydrochloride
Brand: SIGMA

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모든 사진(1)

About This Item

실험식(Hill 표기법):

C₆H₁₄N₂O · HCl

CAS Number:

10466-60-1

Molecular Weight:

166.65

MDL number:

MFCD00070244

UNSPSC 코드:

12352200

PubChem Substance ID:

24896497

분석

≥98% (TLC)

형태

powder

색상

white

SMILES string

Cl.CC(C)CC(N)C(N)=O

InChI

1S/C6H14N2O.ClH/c1-4(2)3-5(7)6(8)9;/h4-5H,3,7H2,1-2H3,(H2,8,9);1H

InChI key

VSPSRRBIXFUMOU-UHFFFAOYSA-N

생화학적/생리학적 작용

DL-Leucinamide hydrochloride is a racemic mixture of D- and L- enantiomers of leucinamide. Leucinamide is an amide derivative of leucine found at the C-terminal of various peptides such as the PAR-2 activating peptide SLIGRL-NH(2).

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

L: -Stereoselective amino acid amidase with broad substrate specificity from Brevundimonas diminuta: characterization of a new member of the leucine aminopeptidase family.

Hidenobu Komeda et al.

Applied microbiology and biotechnology, 70(4), 412-421 (2005-07-08)

Brevundimonas diminuta TPU 5720 produces an amidase acting L-stereoselectively on phenylalaninamide. The enzyme (LaaA(Bd)) was purified to electrophoretic homogeneity by ammonium sulfate fractionation and four steps of column chromatography. The final preparation gave a single band on SDS-PAGE with a

Molecular mechanism of the inhibitory effect of cobalt ion on thermolysin activity and the suppressive effect of calcium ion on the cobalt ion-dependent inactivation of thermolysin.

Yasuhiko Hashida et al.

Journal of biochemistry, 141(6), 879-888 (2007-04-05)

Thermolysin activity in the hydrolysis of N-[3-(2-furyl)acryloyl]-glycyl-l-leucine amide (FAGLA) and FA-l-leucyl-l-alanine amide (FALAA) was examined at various Co(2+) and Ca(2+) concentrations. It decreased to 28% with increasing [Co(2+)] up to 18 mM. The Co(2+)-dependent inactivation was in part suppressed by

Application of Fourier transform infrared spectroscopy for monitoring hydrolysis and synthesis reactions catalyzed by a recombinant amidase.

R Pacheco et al.

Analytical biochemistry, 346(1), 49-58 (2005-09-28)

This study demonstrates the use of Fourier transform infrared (FTIR) spectroscopy for monitoring both synthesis and hydrolysis reactions catalyzed by a recombinant amidase (EC 3.5.1.4) from Pseudomonas aeruginosa. The kinetics of hydrolysis of acetamide, propionamide, butyramide, acrylamide, benzamide, phenylalaninamide, alaninamide

Activation of PAR-2 elicits NO-dependent and CGRP-independent dilation of the dural artery.

Deepak K Bhatt et al.

Headache, 50(6), 1017-1030 (2010-05-22)

The goal of this study was to determine the vascular effects of protease-activated receptor-2 (PAR-2) activation in the rat cranial vasculature. The role of PAR-2 in pain and inflammatory conditions has been established but the information available on its effects

[Marked dissociation of leucine aminopeptidase activities by the use of 2 different substrates--application of the methods to lymphatic diseases].

Y Hirasawa et al.

Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society, 45(5), 907-912 (1982-09-01)

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