L4376

α-Lobeline hydrochloride

~95% (HPLC), powder

• 동의어(들): 2-[6-(2-Hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenylethanone hydrochloride, (−)-Lobeline hydrochloride
• 실험식(Hill 표기법): C₂₂H₂₇NO₂ · HCl
• CAS Number: 134-63-4
• Molecular Weight: 373.92
• Beilstein: 3920196
• EC Number: 205-150-2
• MDL number: MFCD00082455
• UNSPSC 코드: 12352200

속성

• 분석: ~95% (HPLC)
• 양식: powder
• 색상: white to off-white
• solubility: H₂O: 25 mg/mL
• SMILES string: Cl.CN1[C@@H](CCC[C@@H]1CC(=O)c2ccccc2)C[C@H](O)c3ccccc3
• 유전자 정보: human ... SLC18A2(6571)

설명

생화학적/생리학적 작용

Agonist at high-affinity neuronal nicotinic acetylcholine receptors; respiratory stimulant. Inhibits synaptosomal accumulation of dopamine by interaction with the tetrabenazine binding site of the vesicular monoamine transporter (VMAT2). Blocks amphetamine-induced dopamine release.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301 + H331
• 예방조치 성명서: P261 - P264 - P271 - P301 + P310 - P304 + P340 + P311 - P403 + P233
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges