L2011
D-Lactic Dehydrogenase from Lactobacillus leichmannii
ammonium sulfate suspension, ≥250 units/mg protein (biuret)
동의어(들):
Lactate, (R)-Lactate:NAD+ oxidoreductase, D−LDH
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
CAS 번호:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥250 units/mg protein (biuret)
form
ammonium sulfate suspension
Quality Segment
specific activity
≥250 units/mg protein (biuret)
foreign activity
Malic dehydrogenase <0.5% of base activity
storage temp.
2-8°C
General description
Research area: Cell Signalling D-lactate dehydrogenase belongs to the D-isomer-specific 2-hydroxyacid dehydrogenase family. Lactate dehydrogenase (LD) is a tetramer consisting of two (H and M) subunits. It has five isozymes (LD1 to LD5) and this composition varies in different tissues. LD1 is abundant in the kidney, heart, and erythrocytes. LD5 is found in the liver and skeletal muscles. LD is a ubiquitous molecule found in plants, yeast, mammals, and microorganisms and is a member of the oxidoreductase family.
Biochem/physiol Actions
Lactic dehydrogenase (LDH)plays an important role in the glycolytic pathway where it converts pyruvate tolactate by using NAD+ as a co-factor. It is considered animportant molecule that can be used in cancer therapy as it acts as aglycolytic inhibitor. Inhibition of LDH is associated with blocking of aerobicglycolysis in tumour cells.
Physical form
Suspension in 3.2 M (NH4)2SO4, pH 6.0
Other Notes
One unit will reduce 1.0 μmole of pyruvate to D-lactate per min at pH 7.0 at 25 °C.
Still not finding the right product?
Explore all of our products under D-Lactic Dehydrogenase from Lactobacillus leichmannii
저장 등급
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)