생물학적 소스
rat
결합
unconjugated
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
3D10, monoclonal
형태
buffered aqueous solution
분자량
antigen ~60 kDa
종 반응성
mouse, hamster, bovine, canine, rat, human, monkey
기술
microarray: suitable
western blot: 2-4 μg/mL using HeLa cell extract
동형
IgG2a
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... KPNA4(3840)
mouse ... Kpna4(16649)
rat ... Kpna4(361959)
면역원
recombinant mouse importin α3/Qip1.
생화학적/생리학적 작용
The gene KPNA4 (karyopherin subunit α 4) encodes a 16kDa protein, also referred to as importin α 3 belonging to the family of karyopherins (designated KPNA1 to KPNA4), that participates in the recognition of NLS (nuclear localization signal) sites and dock NLS-containing proteins destined for transport into the nuclear pore complex. It binds to translocon and participates in the sorting of INM (inner nuclear membrane)-directed integral membrane proteins. It associates with nucleoporins and functions in cargo-translocation across the nuclear membrane.
물리적 형태
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
KPNA4 Mediates Vitamin D-Dependent Inhibition of NF-kB Activity in Swine Epicardial Preadipocytes.
Chen S
Circulation, A12818-A12818 (2014)
Sharon C Braunagel et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(22), 9307-9312 (2007-05-23)
Spodoptera frugiperda (Sf9) importin-alpha-16 is a translocon-associated protein that participates in the early sorting pathway of baculovirus integral membrane proteins destined for the inner nuclear membrane (INM). To discern whether sorting intermediate protein complexes like those observed in insect cells
Annett Koch et al.
Cell cycle (Georgetown, Tex.), 10(8), 1200-1207 (2011-03-18)
It is well established that mutual relations exist between the oxidative status of a cell and the ubiquitin proteasome system (UPS). Oxidation of proteins leads to misfolding and thus claims a higher proteolytic activity of the UPS to dispose these
Matthew Frieman et al.
Journal of virology, 81(18), 9812-9824 (2007-06-29)
The host innate immune response is an important deterrent of severe viral infection in humans and animals. Nuclear import factors function as key gatekeepers that regulate the transport of innate immune regulatory cargo to the nucleus of cells to activate
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