모든 사진(1)

주요 문서

COO/COA

모든 문서 보기

H7149

(±)-6-Hydroxy-3,4-methylenedioxymethamphetamine

Name: (±)-6-Hydroxy-3,4-methylenedioxymethamphetamine
Brand: SIGMA

동의어(들):

6-Hydroxy-MDMA

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모든 사진(1)

About This Item

실험식(Hill 표기법):

C₁₁H₁₅NO₃

CAS Number:

138808-79-4

Molecular Weight:

209.24

MDL number:

MFCD00171438

UNSPSC 코드:

12352200

PubChem Substance ID:

329815241

약물 제어

regulated under CDSA - not available from Sigma-Aldrich Canada

저장 온도

2-8°C

SMILES string

CNC(C)Cc1cc2OCOc2cc1O

InChI

1S/C11H15NO3/c1-7(12-2)3-8-4-10-11(5-9(8)13)15-6-14-10/h4-5,7,12-13H,3,6H2,1-2H3

InChI key

RQQIIXFYTHWFKW-UHFFFAOYSA-N

생화학적/생리학적 작용

A metabolite of MDMA

픽토그램

GHS06

신호어

Danger

유해 및 위험 성명서

H300 + H310 + H330

예방조치 성명서

P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Long-term alteration in the central monoaminergic systems of the rat by 2,4,5-trihydroxyamphetamine but not by 2-hydroxy-4,5-methylenedioxymethamphetamine or 2-hydroxy-4,5-methylenedioxyamphetamine.

I Elayan et al.

European journal of pharmacology, 221(2-3), 281-288 (1992-10-20)

The long-term effects of three metabolites of 3,4-methylenedioxymethamphetamine (MDMA) on the central monoaminergic systems of the rat were examined. Seven days after the intracerebroventricular administration of 0.25 and 0.5 mumol 2,4,5-trihydroxyamphetamine, hippocampal tryptophan hydroxylase (TPH) activity was reduced to 5

Disposition of methylenedioxymethamphetamine and three metabolites in the brains of different rat strains and their possible roles in acute serotonin depletion.

T Chu et al.

Biochemical pharmacology, 51(6), 789-796 (1996-03-22)

3,4-Methylenedioxymethamphetamine (MDMA) affects both dopamine and serotonin (5-HT) systems. One of its acute actions is to cause a reversible fall in steady-state brain 5-HT concentrations. To investigate the chemical basis of this acute effect, the brain levels of the parent

The neurotoxic effects of methylenedioxymethamphetamine (MDMA) and its metabolites on rat brain spheroids in culture.

T M Walker et al.

Cell biology and toxicology, 15(3), 137-142 (1999-12-02)

Rat whole-brain spheroids were used to assess the intrinsic neurotoxicity of methylenedioxy-methamphetamine (MDMA, Ecstasy) and two of its metabolites, dihydroxymethamphetamine (DHMA) and 6-hydroxy-MDMA (6-OH MDMA). Exposure of brain spheroids to MDMA or the metabolite 6-OH MDMA (up to 500 micromol/L)

Lim, H.K. and Foltz, R.L.

Biomedical Mass Spectrometry, 20, 677-677 (1991)

In vivo formation of aromatic hydroxylated metabolites of 3,4-(methylenedioxy)methamphetamine in the rat: identification by ion trap tandem mass spectrometric (MS/MS and MS/MS/MS) techniques.

H K Lim et al.

Biological mass spectrometry, 20(11), 677-686 (1991-11-01)

Aromatic hydroxylation has been established as a pathway for the in vivo metabolism of 3,4-(methylenedioxy)methamphetamine (MDMA) in the rat. Hydroxylation occurred at positions 2, 5 and 6 of the 3,4-methylenedioxyphenyl ring, but is favored at the 6 position. All three

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