H6034

L-Histidine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications

• 동의어(들): (S)-2-Amino-3-(4-imidazolyl)propionic acid, NSC 137773
• 실험식(Hill 표기법): C₆H₉N₃O₂
• CAS Number: 71-00-1
• Molecular Weight: 155.15
• Beilstein: 84088
• EC Number: 200-745-3
• MDL number: MFCD00064315
• UNSPSC 코드: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895728
• NACRES: NA.26

속성

• product name: L-Histidine, suitable for cell culture, meets EP, USP testing specifications, from non-animal source
• 생물학적 소스: non-animal source
• Agency: meets EP testing specifications; meets USP testing specifications
• 분석: 98.5-101.0%
• 형태: powder
• 광학 활성: [α]20/D 12.0 to 12.8 °, c = 11 in 6 M HCl; [α]25/D 12.6 to 14.0 °, c = 11 in 6 M HCl
• 기술: cell culture | mammalian: suitable
• 불순물: endotoxin, tested
• 색상: white to off-white
• mp: 282 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• 양이온 미량물: As: ≤1 ppm; Fe: ≤10 ppm; NH₄⁺: <0.02%
• 응용 분야: peptide synthesis; pharmaceutical (small molecule)
• 작용기: (Imidazole); amine; carboxylic acid
• 저장 온도: room temp
• SMILES string: N[C@@H](Cc1c[nH]cn1)C(O)=O
• InChI: 1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: HNDVDQJCIGZPNO-YFKPBYRVSA-N
• 유전자 정보: human ... CA1(759) , CA2(760)

설명

일반 설명

L-Histidine is a proteinogenic amino acid and an essential amino acid required for histamine production. This positively charged amino acid is vital for growth, tissue repair, myelin sheath maintenance, and histamine synthesis. Histamine plays critical roles in immunity, gastric secretion, and more. L-Histidine is essential for blood cell production and tissue protection against radiation and heavy metals. L-Histidine plays a role as a metabolite and also acts as a cofactor in enzyme protection during protein synthesis. It is an L-enantiomer of histidine and is necessary for histamine synthesis and human development. L-Histidine finds applications in cell culture, metabolomics and biochemical research.

애플리케이션

L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-FC) for the selection of yeast transformants. It has also been used as a component of adult mouse keratinocyte growth medium.

생화학적/생리학적 작용

L-Histidine is an essential amino acid that binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.

Precursor of histamine by action of histidine decarboxylase.

특징 및 장점

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

기타 정보

For additional information on our range of Biochemicals, please complete this form.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)