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Merck
모든 사진(1)

문서

GW22651

Sigma-Aldrich

Anti-Spondin-1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

chicken

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

종 반응성

human, rat, mouse

제조업체/상표

Genway 15-288-22651

기술

western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... SPON1(10418)

면역원

Immunogen Sequence: GI # 24307905, sequence 549-807
Recombinant spondin 1, extracellular matrix protein

애플리케이션

Anti-Spondin-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

생화학적/생리학적 작용

Spondin-1 (also known as F-spondin) is a protein encoded by the SPON1 gene in humans. It is an extracellular matrix protein that mediates axon guidance during neuronal development and consists of an N-terminal domain called as reelin-N domain. F-spondin highly expressing human periodontal ligament (HPL) cells show similar phenotype of cementoblasts. It acts as a promoting factor for cementoblastic differentiation.

물리적 형태

Solution in phosphate buffered saline containing 0.02% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


시험 성적서(COA)

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문서 라이브러리 방문

Kemin Tan et al.
Journal of molecular biology, 381(5), 1213-1223 (2008-07-08)
The extracellular matrix protein F-spondin mediates axon guidance during neuronal development. Its N-terminal domain, termed the reelin-N domain, is conserved in F-spondins, reelins, and other extracellular matrix proteins. In this study, a recombinant human reelin-N domain has been expressed, purified
Masae Kitagawa et al.
Biochemical and biophysical research communications, 349(3), 1050-1056 (2006-09-13)
Cementum is a mineralized tissue produced by cementoblasts covering the roots of teeth that provides for the attachment of periodontal ligament to roots and surrounding alveolar bone. To study the mechanism of proliferation and differentiation of cementoblasts is important for

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