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Merck
모든 사진(1)

주요 문서

G7160

Sigma-Aldrich

Galanin Fragment 1-13-Spantide I

≥95% (HPLC)

동의어(들):

C7

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C138H199N35O30
CAS Number:
143868-20-6
Molecular Weight:
2828.27
MDL number:
MFCD00273999
UNSPSC 코드:
12352200

분석

≥95% (HPLC)

UniProt 수납 번호

P22466
Q9UBC7

저장 온도

−20°C

유전자 정보

human ... GAL(51083) , GALP(85569)

Amino Acid Sequence

Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-D-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Leu-NH2

생화학적/생리학적 작용

Tandem-linked peptide which acts as a potent galanin receptor antagonist

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

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문서 라이브러리 방문

L G Ulman et al.
Regulatory peptides, 51(1), 17-23 (1994-04-14)
Previous studies have shown that injection of galanin (GAL: 6.2 nmol/kg) causes prolonged inhibition of cardiac vagal action in anaesthetised cats. Stimulation of the cardiac sympathetic nerve (16 Hz for 5 min) also produces inhibition of cardiac vagal action, an
I Kisfalvi et al.
Journal of physiology, Paris, 94(1), 37-42 (2000-04-13)
The neuropeptide galanin has been reported to have a wide range of biological actions both in the central nervous system and in the gastrointestinal tract. Recent works led to the discovery of selective galanin receptor antagonists including M15 (galanin(1-12)-Pro-substanceP(5-11)-amide), M35
D A Mahns et al.
Regulatory peptides, 67(3), 163-168 (1996-12-17)
Galanin is a neuropeptide that causes a marked pressor response in several non-mammalian vertebrate species, and some marsupials. In this study, the effect of three galanin antagonists were tested on the pressor response to an intravenous dose (6.3 nmol/kg) of
I Kisfalvi et al.
Journal of physiology, Paris, 95(1-6), 385-389 (2001-10-12)
Galanin is a neuropeptide having a wide range of biological actions. Recently selective galanin receptor antagonists such as M35 [galanin(1-12)-Pro-bradykinin(2-9)-amide] and C7 [galanin(1-12)-Pro-spantide-amide] have been described. These antagonists have blocked the actions of galanin on flexor reflex, glucose-induced insulin secretion
R L Corwin et al.
The European journal of neuroscience, 5(11), 1528-1533 (1993-11-01)
Galanin significantly increased food intake when microinjected into the region of the central nucleus of the amygdala as well as into the paraventricular nucleus of the hypothalamus. In the amygdala this effect was specific to feeding; no change in grooming
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