D7071

Dapoxetine hydrochloride

≥98% (HPLC)

• 동의어(들): (S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride, S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride
• 실험식(Hill 표기법): C₂₁H₂₃NO · HCl
• CAS Number: 129938-20-1
• Molecular Weight: 341.87
• MDL number: MFCD08272809
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329798842
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: powder
• 광학 활성: [α]/D +125 to +135°, c = 1 in methanol
• 저장 조건: desiccated
• 색상: white
• solubility: DMSO: ≥20 mg/mL
• 주관자: Eli Lilly
• 저장 온도: room temp
• SMILES string: Cl.CN(C)[C@@H](CCOc1cccc2ccccc12)c3ccccc3
• InChI: 1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1
• InChI key: IHWDIQRWYNMKFM-BDQAORGHSA-N
• 유전자 정보: human ... SLC6A4(6532)

설명

일반 설명

Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.

생화학적/생리학적 작용

Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe.

Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation

특징 및 장점

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302,H319,H413
• 예방조치 성명서: P264 - P273 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable