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Merck
모든 사진(1)

주요 문서

D003

Sigma-Aldrich

R(−)-Apocodeine hydrochloride

solid

동의어(들):

R(−)-10-Methoxy-11-hydroxyaporphine hydrochloride

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About This Item

실험식(Hill 표기법):
C18H19NO2 · HCl
CAS Number:
Molecular Weight:
317.81
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:

양식

solid

광학 활성

[α]22/D −43° in methanol(lit.)

색상

off-white

solubility

H2O: soluble

저장 온도

2-8°C

SMILES string

Cl[H].[H][C@]12Cc3ccc(OC)c(O)c3-c4cccc(CCN1C)c24

생화학적/생리학적 작용

Dopamine receptor agonist; apomorphine metabolite.

주의사항

Photosensitive

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

R van der Geest et al.
Journal of chromatography. B, Biomedical sciences and applications, 702(1-2), 131-141 (1998-02-04)
Analytical methods are described for the selective, rapid and sensitive determination of R- and S-apomorphine, apocodeine and isoapocodeine and the glucuronic acid and sulfate conjugates in plasma and urine. The methods involve liquid-liquid extraction followed by high-performance liquid chromatography with
Gessa, et al., eds.
Apomorphine and Other Dopaminomimetics, Vols. 1 and 2 (1981)
R V Smith et al.
Journal of natural products, 46(1), 79-91 (1983-01-01)
A solid basis for the M4-approach has been developed over the past 10 years. Recent examples of the production of difficult-to-synthesize mammalian metabolites through microbial transformations attest to the utility of the methodology. There is, however, much more to be
K Ishige et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 21(16), 6069-6076 (2001-08-07)
Oxidative stress is thought to be the cause of nerve cell death in many CNS pathologies, including ischemia, trauma, and neurodegenerative disease. Glutamate kills nerve cells that lack ionotropic glutamate receptors via the inhibition of the cystine-glutamate antiporter x(c)(-), resulting
Frédéric Libert et al.
Journal of mass spectrometry : JMS, 40(12), 1521-1525 (2005-11-15)
A method was developed and validated for the analysis of R(-)-apomorphine, (R-)-apocodeine and R(-)-norapomorphine in human plasma and urine with N-propylnorapomorphine as internal standard using gas chromatography/mass spectrometry (GC/MS) and single-ion monitoring after a single liquid-liquid extraction and silylation of

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