The B9059 BACE-1 product included in the kit, serves as a positive control. The Technical Bulletin notes that the concentration of this item is approximate 3 units/microliter. This material has not been tested for purity. Therefore, a molar concentration cannot be provided.
CS0010
β-Secretase (BACE1) Activity Detection Kit (Fluorescent)
1 kit sufficient for 250 reactions
동의어(들):
BACE1 Activity Detection Kit (Fluorescent)
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
| 팩 크기/SKU | 재고 정보 | 가격 (VAT 별도) |
|---|---|---|
1 kit | 오늘 배송 가능재고 수량 조회Seoul Warehouse South Korea | ₩2,739,282 |
제품정보 (DICE 배송 시 비용 별도)
NACRES:
NA.84
UNSPSC Code:
12161503
Quality Segment
usage
kit sufficient for 250 reactions
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... BACE1(23621)
Application
The kit provides all the reagents required for an efficient detection of BACE1 activity. It contains an enzyme to be used for screening for potential BACE1 inhibitors. The assay is based on the fluorescence resonance energy transfer (FRET) method in which the fluorescence signal enhancement is observed after substrate cleavage by BACE1.
Biochem/physiol Actions
BACE1 is a transmembrane protease responsible for the β site cleavage of the amyloid precursor protein (APP) to produce amyloid β peptide (Aβ). The accumulation of Aβ in the brain is a primary cause for the progression of Alzheimer′s. BACE1 is a target for inhibitor drug discovery.
1 of 1
이 품목 | |||
|---|---|---|---|
| description 1 kit sufficient for 250 reactions | description recombinant, expressed in HEK 293 cells (C-terminal FLAG tagged), ≥10,000 units/mg protein | description Chemicon®, from rabbit | description clone 61-3E7, Chemicon®, from mouse |
| Quality Level 300 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| usage kit sufficient for 250 reactions | usage - | usage - | usage - |
| Gene Information human ... BACE1(23621) | Gene Information human ... BACE1(23621) | Gene Information human ... BACE1(23621) | Gene Information human ... BACE1(23621) |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
| shipped in wet ice | shipped in wet ice | shipped in wet ice | shipped in wet ice |
키트 구성품 전용
제품 번호
설명
- Fluorescent Assay Buffer 50 mL
- Stop Solution 15 mL
- Substrate (MOCA-SEV-NL-DAEFR-DNP-RR) 500 μL
- Assay Standard 140 μL
- BACE1 (β−Secretase) 300 units 100 μL
저장 등급
10 - Combustible liquids
wgk
WGK 3