생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
종 반응성
human
재고 정보
not available in Japan
농도
~1 mg/mL
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
유전자 정보
human ... CCR7(1236)
mouse ... Ccr7(12775)
rat ... Ccr7(287673)
면역원
synthetic peptide corresponding to the C-terminal domain of human C-C chemokine receptor 7 (CCR7), conjugated to KLH.
생화학적/생리학적 작용
CCR-7 is a G protein-coupled receptor that activates B and T lymphocytes. It mediates the effects of Epstein-Barr virus on B lymphocytes, regulates the migration of memory T cells to sites of inflammation and stimulates dendritic cell maturation.
물리적 형태
Solution in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
American journal of respiratory cell and molecular biology, 48(6), 758-764 (2013-03-02)
Human eosinophils display directed chemotactic activity toward an array of soluble chemokines. Eosinophils have been observed to migrate to draining lymph nodes in experimental models of allergic inflammation, yet it is unknown whether eosinophils express CCR7, a key chemokine receptor
Journal of cell science, 125(Pt 19), 4463-4474 (2012-07-17)
The chemokine receptor CCR7 is essential for lymphocyte and dendritic cell homing to secondary lymphoid organs. Owing to the ability to induce directional migration, CCR7 and its ligands CCL19 and CCL21 are pivotal for the regulation of the immune system.
Immunology letters, 146(1-2), 70-73 (2012-06-05)
Prostaglandin E(2) (PGE(2)) induces the expression of C-C chemokine receptor type 7 (CCR7) on human monocytes, thereby enabling their subsequent migration in response to CCL19 and CCL21, the natural ligands for CCR7. To date, important mediators of PGE(2)-mediated monocyte migration
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