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Merck
모든 사진(1)

주요 문서

B9684

Sigma-Aldrich

Anti-Brn3a antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Brn3A Antibody, Brn3A Antibody - Anti-Brn3a antibody produced in rabbit, Anti-FLJ13449, Anti-OCT-T1, Anti-POU4F1, Anti-RDC1

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

buffered aqueous solution

분자량

antigen 42.9 kDa

종 반응성

human

종 반응성(상동성에 의해 예측)

mouse

기술

immunocytochemistry: 1:200-1:1000
immunohistochemistry (frozen sections): 1:200-1:1000
western blot: 1:200-1:1000

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... POU4F1(5457)
mouse ... Pou4f1(18996)
rat ... Pou4f1(114503)

일반 설명

Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons.

면역원

POU4F1 / BRN3A antibody was raised against synthetic peptide (aa 141-157, AGGGGAHDGPGGGGGPG) corresponding to human Brn3a (BSA conjugated). Percent identity by BLAST analysis: Human (100%); Mouse (94%); Drosophila (82%).

Epitope
aa141-157

물리적 형태

Supplied in phosphate buffered saline, pH 7.4

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Brenna Krieger et al.
PloS one, 12(7), e0180091-e0180091 (2017-07-29)
The retina communicates with the brain using ≥30 parallel channels, each carried by axons of distinct types of retinal ganglion cells. In every mammalian retina one finds so-called "alpha" ganglion cells (αRGCs), identified by their large cell bodies, stout axons
Peter Stacey et al.
SLAS discovery : advancing life sciences R & D, 23(6), 585-596 (2018-03-17)
Screening against a disease-relevant phenotype to identify compounds that change the outcome of biological pathways, rather than just the activity of specific targets, offers an alternative approach to find modulators of disease characteristics. However, in pain research, use of in
RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury.
Seyed Hosseini Fin, et al.
Frontiers in Cellular Neuroscience, 17, 1156084-1156084 (2023)
Fuxin Shi et al.
The European journal of neuroscience, 26(11), 3016-3023 (2007-11-17)
In mammals, hair cells and auditory neurons lack the capacity to regenerate, and damage to either cell type can result in hearing loss. Replacement cells for regeneration could potentially be made by directed differentiation of human embryonic stem (hES) cells.
Hans Jürgen Wester et al.
Theranostics, 5(6), 618-630 (2015-04-01)
Chemokine ligand-receptor interactions play a pivotal role in cell attraction and cellular trafficking, both in normal tissue homeostasis and in disease. In cancer, chemokine receptor-4 (CXCR4) expression is an adverse prognostic factor. Early clinical studies suggest that targeting CXCR4 with

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