라벨링 범위
~6% Br (by weight)
저장 온도
−20°C
애플리케이션
2-Bromostearate acid (bromonucleic acid) is used to inhibit fatty acid oxidation. 2-Bromostearate acid is a mitochondrial carnitine palmitoyltransferase I (CPT I) inhibitor.
제조 메모
Bromination of yeast RNA.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Effect of 2-bromostearate on glucose-phosphorylating activities and the dynamics of insulin secretion in islets of Langerhans during fasting.
Bedoya FJ, Ramirez R, Arilla E, Goberna R.
Diabetes, 33, 858-863 (1084)
C R Bliss et al.
The American journal of physiology, 263(5 Pt 1), E890-E896 (1992-11-01)
The development of glucose-stimulated insulin release and time-dependent potentiation (TDP) has been studied in isolated islets from 7-, 14-, and 21-day-old and 3-mo-old rats. Responses were small at 7 days and changed little at 14 days. At 21 days the
S Chen et al.
Diabetes, 43(7), 878-883 (1994-07-01)
We sought to explore the emerging concept that malonyl-CoA generation, with concomitant suppression of mitochondrial carnitine palmitoyltransferase I (CPT I), represents an important component of glucose-stimulated insulin secretion (GSIS) by the pancreatic beta-cell (Prentki M, Vischer S, Glennon MC, Regazzi
J Tamarit-Rodriguez et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 16(3), 115-119 (1984-03-01)
The hypothesis was made of an increased oxidation of fatty acids (FFA) and a decrease of their esterification rate contributing to the islet secretory defect during starvation. 2-Bromostearate (BrS), a FFA-oxidation inhibitor, was therefore tested on the islet secretion of
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