AV36668
Anti-MCM8 antibody produced in rabbit
affinity isolated antibody
동의어(들):
Anti-C20orf154, Anti-MGC119522, Anti-MGC119523, Anti-MGC12866, Anti-MGC4816, Anti-Minichromosome maintenance complex component 8, Anti-REC, Anti-dJ967N21.5
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
94 kDa
종 반응성
bovine, rabbit, human, guinea pig, horse, rat, mouse
농도
0.5 mg - 1 mg/mL
기술
immunohistochemistry: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MCM8(84515)
관련 카테고리
면역원
Synthetic peptide directed towards the C terminal region of human MCM8
생화학적/생리학적 작용
Minichromosome maintenance complex component 8 (MCM8) is one of the mini-chromosome maintenance proteins that are crucial for eukaryotic genome replication. MCM proteins are key components of the pre-replication complex, recruit replication-related proteins and form replication forks. MCM8 complexes with MCM9 to recruit RAD51 at the sites of DNA damage to facilitate homologous recombination.
서열
Synthetic peptide located within the following region: IRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQH
물리적 형태
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
The dimeric Mcm8-9 complex of Xenopus laevis likely has a conserved function for resistance to DNA damage.
Masato T Kanemaki
Cell cycle (Georgetown, Tex.), 12(9), 1338-1339 (2013-04-17)
Jonghoon Park et al.
Molecular and cellular biology, 33(8), 1632-1644 (2013-02-13)
The minichromosome maintenance protein homologs MCM8 and MCM9 have previously been implicated in DNA replication elongation and prereplication complex (pre-RC) formation, respectively. We found that MCM8 and MCM9 physically associate with each other and that MCM8 is required for the
Matthew L Bochman et al.
Microbiology and molecular biology reviews : MMBR, 73(4), 652-683 (2009-12-01)
The Mcm2-7 complex serves as the eukaryotic replicative helicase, the molecular motor that both unwinds duplex DNA and powers fork progression during DNA replication. Consistent with its central role in this process, much prior work has illustrated that Mcm2-7 loading
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