AV32362
Anti-TLE3 antibody produced in rabbit
IgG fraction of antiserum
동의어(들):
Anti-Transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
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모든 사진(1)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
결합:
unconjugated
application:
WB
클론:
polyclonal
종 반응성:
pig, dog, human, bovine
citations:
2
기술:
western blot: suitable
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
IgG fraction of antiserum
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
83 kDa
종 반응성
pig, dog, human, bovine
농도
0.5 mg - 1 mg/mL
기술
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TLE3(7090)
일반 설명
TLE3 is known to function as a transcriptional coregulator of adipogenesis. It interacts with HESX1 and PROP1 to regulate transcriptional expression.
Rabbit Anti-TLE3 antibody recognizes human, zebrafish, rat, mouse, and canine TLE3.
Rabbit Anti-TLE3 antibody recognizes human, zebrafish, rat, mouse, and canine TLE3.
면역원
Synthetic peptide directed towards the N terminal region of human TLE3
애플리케이션
Rabbit Anti-TLE3 antibody can be used for western blot applications at a concentration of 2.5μg/ml.
생화학적/생리학적 작용
The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.
서열
Synthetic peptide located within the following region: GSSSGLLALGALGSQAHLTVKDEKNHHELDHRERESSANNSVSPSESLRA
물리적 형태
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Luciani R Carvalho et al.
Molecular endocrinology (Baltimore, Md.), 24(4), 754-765 (2010-02-26)
Pituitary hormone deficiency causes short stature in one in 4000 children born and can be caused by mutations in transcription factor genes, including HESX1, PROP1, and POU1F1. HESX1 interacts with a member of the groucho-related gene family, TLE1, through an
Claudio J Villanueva et al.
Cell metabolism, 13(4), 413-427 (2011-04-05)
PPARγ and Wnt signaling are central positive and negative regulators of adipogenesis, respectively. Here we identify the groucho family member TLE3 as a transcriptional integrator of the PPARγ and Wnt pathways. TLE3 is a direct target of PPARγ that participates
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