A9102

AH13205

≥98% (HPLC), oil

• 동의어(들): trans-2-(4-(1-Hydroxyhexyl)phenyl-5-oxocyclopentaneheptanoic acid
• 실험식(Hill 표기법): C₂₄H₃₆O₄
• CAS Number: 148436-63-9
• Molecular Weight: 388.54
• MDL number: MFCD00797641
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329771031
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: oil
• 색상: pale yellow
• solubility: DMSO: >10 mg/mL
• 주관자: GlaxoSmithKline
• 저장 온도: −20°C
• SMILES string: CCCCCC(O)c1ccc(cc1)[C@H]2CCC(=O)[C@@H]2CCCCCCC(O)=O
• InChI: 1S/C24H36O4/c1-2-3-6-10-22(25)19-14-12-18(13-15-19)20-16-17-23(26)21(20)9-7-4-5-8-11-24(27)28/h12-15,20-22,25H,2-11,16-17H2,1H3,(H,27,28)/t20-,21-,22?/m1/s1
• InChI key: XMQKDOCUWFCMEJ-JAZPPYFYSA-N

설명

일반 설명

AH13205 is EP₂ prostanoid receptor agonist. There are five types of prostanoid receptors, which are classified based on sensitivity to the five naturally-occuring prostanoid ligand. The EP type of receptor is further divided into four subgroups – EP₁, EP₂, EP₃ and EP₄. EP₂ activation results in vascular, bronchial and reproductive smooth muscle relaxation.

생화학적/생리학적 작용

AH13205 is a selective, low potency agonist for the EP₂ receptor. AH13205 has been shown to compete with Prostaglandin E2 (PGE2) for binding, resulting in the displacement of PGE2 binding.

특징 및 장점

This compound is featured on the Prostanoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)