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Merck
모든 사진(1)

문서

A4469

Sigma-Aldrich

Monoclonal Anti-ACTR/AIB1 antibody produced in mouse

clone AX 15, ascites fluid

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

결합

unconjugated

항체 형태

ascites fluid

항체 생산 유형

primary antibodies

클론

AX 15, monoclonal

분자량

antigen 150 kDa

포함

0.035% sodium azide
30% glycerol

종 반응성

human

기술

immunoprecipitation (IP): 15 μL using 500 μg of a BG-1 ovarian cell RIPA lysate.
western blot (chemiluminescent): 1:500 using RIPA lysates of BG-1 ovarian cancer cells

동형

IgG

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... NCOA3(8202)

일반 설명

ACTR associates with estrogen receptors in breast and ovarian cancers and stimulates transcription. Hence, ACTR has been implicated in the carcinogenesis of breast and ovarian tumors. Mouse monoclonal Anti-ACTR/AIB1 antibody recognizes human ACTR (150kD) and another doublet (110kD) by immunoblotting.
ACTR, a nuclear receptor coactivator, is also referred to as amplified in breast cancer 1 (AIB1), thyroid hormone receptor activator molecule-1 (TRAM-1), receptor-associated coactivator 3 (RAC3 and SRC3).

면역원

GST fusion protein containing amino acids 605-1294 of human ACTR.

애플리케이션

Mouse monoclonal can be used for immunoprecipitation (15μL using 500μg of a BG-1 ovarian cell RIPA lysate) and western blot (1:500, using RIPA lysates of BG-1 ovarian cancer cells) assays.

물리적 형태

The product is supplied as mouse ascites fluid, containing 30% glycerol and 0.035% sodium azide

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids


시험 성적서(COA)

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문서 라이브러리 방문

S L Anzick et al.
Science (New York, N.Y.), 277(5328), 965-968 (1997-08-15)
Members of the recently recognized SRC-1 family of transcriptional coactivators interact with steroid hormone receptors to enhance ligand-dependent transcription. AIB1, a member of the SRC-1 family, was cloned during a search on the long arm of chromosome 20 for genes

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