A3097

[Pro¹⁸, Asp²¹]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

• 실험식(Hill 표기법): C₃₃H₄₃N₅O₈
• CAS Number: 182912-74-9
• Molecular Weight: 637.72
• MDL number: MFCD01862668
• UNSPSC 코드: 12352200

속성

• 분석: ≥98% (HPLC)
• 양식: solid
• UniProt 수납 번호: P05067
• 저장 온도: −20°C
• SMILES string: CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O
• 유전자 정보: human ... APP(351)

설명

Amino Acid Sequence

Leu-Pro-Phe-Phe-Asp

생화학적/생리학적 작용

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.