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Merck
모든 사진(1)

문서

A271

Sigma-Aldrich

Anti-α2A Adrenergic Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

동의어(들):

Anti-ADRA2, Anti-ADRA2R, Anti-ADRAR, Anti-ALPHA2AAR, Anti-ZNF32

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen ~45 kDa

종 반응성

rat, human, mouse, pig

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1000
western blot: 1:500

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... ADRA2A(150)
mouse ... Adra2a(11551)
rat ... Adra2a(25083)

일반 설명

Adrenergic receptors (ARs) belong to the 7-transmembrane domain G protein-coupled receptor superfamily that binds to the endogenous catecholamines, epinephrine and norepinephrine. α2AR subtypes block adenylyl cyclase, suppress voltage-sensitive Ca2+ channels, and stimulate receptor dependent K+ channels. All of the α2AR subtypes inhibit adenylyl cyclase through coupling to members of the Gi/Go class of G proteins. They are an important component of the neural circuitry and modulate cardiovascular physiology. The physiological function of the α2ARs in the kidney is to regulate Na+/H+ exchange.
Anti-α2A adrenergic receptor detects rat and mouse α2A adrenergic receptors by immunoblotting and immunohistochemistry. In immunoblotting, the antibody detects an approx. 45kDa band representing α2A receptors in tissues expressing this receptor subtype, although some non-specific bands have also been observed in certain cases.

면역원

synthetic peptide derived from amino acids 218-235 of human, mouse, rat, and pig α2A adrenergic receptor. The immunogen sequence is found within the third intracellular loop of the α2A adrenergic receptor subtype.

애플리케이션

Rabbit anti-α2A adrenergic receptor antibody can be used for western blot (1:500) and immunohistochemistry (1:1000) applications.

물리적 형태

Solution in phosphate buffered saline, containing 1 mg/ml BSA and 0.05% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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