A1164
Azaserine
Hybri-Max™, γ-irradiated, 50x, lyophilized powder, BioXtra, suitable for hybridoma
동의어(들):
O-Diazoacetyl-L-serine
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C5H7N3O4
CAS Number:
Molecular Weight:
173.13
Beilstein:
1726602
EC Number:
MDL number:
UNSPSC 코드:
12352207
PubChem Substance ID:
NACRES:
NA.75
추천 제품
Grade
Hybri-Max™
Quality Level
무균
γ-irradiated
제품 라인
BioXtra
형태
lyophilized powder
기술
cell culture | hybridoma: suitable
불순물
endotoxin, tested
항생제 활성 스펙트럼
fungi
동작 모드
enzyme | inhibits
저장 온도
−20°C
SMILES string
N[C@@H](COC(=O)C=[N+]=[N-])C(O)=O
InChI
1S/C5H7N3O4/c6-3(5(10)11)2-12-4(9)1-8-7/h1,3H,2,6H2,(H,10,11)/t3-/m0/s1
InChI key
MZZGOOYMKKIOOX-VKHMYHEASA-N
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일반 설명
Chemical structure: amino acid derivatives
애플리케이션
For use in hybridoma cell culture applications as a myeloma selection agent. Used to study inhibition of formylglycinamide ribonucleotide amidotransferase and PRPP amidotransferase.
생화학적/생리학적 작용
Azaserine is an antibiotic, generated by Streptomyces fragilis. It is considered as a potential mutation inducing agent. It is known to promote pancreatic cancer and induces adenoma and carcinoma in vivo and in vitro. Azaserine also stimulates kidney and liver tumors in rats.
재구성
Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium. Final working concentration: 5.7 μM azaserine.
법적 정보
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
신호어
Danger
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Antineoplastic and Immunosuppressive Agents, Part 2, 494-494 (2013)
Kei Wada et al.
Journal of molecular biology, 380(2), 361-372 (2008-06-17)
gamma-Glutamyltranspeptidase (GGT) catalyzes the cleavage of such gamma-glutamyl compounds as glutathione, and the transfer of their gamma-glutamyl group to water or to other amino acids and peptides. GGT is involved in a number of biological phenomena such as drug resistance
The Pathobiology of Neoplasia, 154-154 (2012)
Céline Masclaux-Daubresse et al.
Plant physiology, 140(2), 444-456 (2006-01-13)
Glutamate (Glu) metabolism and amino acid translocation were investigated in the young and old leaves of tobacco (Nicotiana tabacum L. cv Xanthi) using [15N]ammonium and [2-15N]Glu tracers. Regardless of leaf age, [15N]ammonium assimilation occurred via glutamine synthetase (GS; EC 6.1.1.3)
A J Almeida et al.
Fungal genetics and biology : FG & B, 44(12), 1387-1398 (2007-05-22)
We herein report the development of a molecular toolbox for the dimorphic fungus Paracoccidioides brasiliensis, specifically a more efficient transformation and a gene expression system. We evaluated several parameters that influence Agrobacterium tumefaciens-mediated transformation (ATMT), such as co-cultivation conditions and
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