모든 사진(1)
About This Item
실험식(Hill 표기법):
C13H12N4O5S · xH2O
CAS Number:
Molecular Weight:
336.32 (anhydrous basis)
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
추천 제품
분석
≥98% (HPLC)
양식
solid
색상
white
solubility
DMSO: >10 mg/mL
H2O: 12 mg/mL
ethanol: 12 mg/mL
0.1 M HCl: 15 mg/mL
SMILES string
O.CN1C(=O)N(C)c2nc([nH]c2C1=O)-c3ccc(cc3)S(O)(=O)=O
InChI
1S/C13H12N4O5S.H2O/c1-16-11-9(12(18)17(2)13(16)19)14-10(15-11)7-3-5-8(6-4-7)23(20,21)22;/h3-6H,1-2H3,(H,14,15)(H,20,21,22);1H2
InChI key
AYQOEZBHENEBEJ-UHFFFAOYSA-N
유전자 정보
human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140)
rat ... Adora1(29290) , Adora2a(25369)
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생화학적/생리학적 작용
Polar adenosine receptor antagonist, which penetrates cells to a limited extent and is relatively soluble in water.
재구성
Solutions may be stored for several days at 4 °C.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
Patrik Aronsson et al.
Basic & clinical pharmacology & toxicology, 107(1), 603-613 (2010-04-22)
The aim of the present study was to assess the purinoceptor functional responses of the urinary bladder by using isolated rat urinary bladder strip preparations. ATP elicited a transient bladder contraction followed by a sustained relaxation and ADP, UDP and
Eric M George et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 299(6), R1629-R1633 (2010-10-22)
The role of adenosine in the regulation of cardiovascular function has long been acknowledged, but only recently has its importance in angiogenesis been appreciated, most notably, through its direct regulation of the proangiogenic growth factor, VEGF. Recent work has established
Marta Paiva et al.
Journal of cardiovascular pharmacology, 53(5), 373-378 (2009-03-20)
Metformin improves cardiovascular outcomes in patients with type 2 diabetes compared with other glucose-lowering drugs. Experimental studies have shown that metformin can increase the intracellular concentration of adenosine monophosphate, which is a major determinant of the intracellular formation of adenosine.
Kimberley E Wever et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 26(10), 3108-3117 (2011-03-24)
Remote ischaemic preconditioning (RIPC) is a strategy to protect a target organ against ischaemia-reperfusion injury (IRI) by inducing short-term ischaemia/reperfusion (I/R) in a remote organ. RIPC of the kidney by temporary limb occlusion would be a safe, inexpensive and noninvasive
Claudia Penna et al.
The Journal of surgical research, 153(2), 231-238 (2008-08-13)
Postconditioning (PostC) maneuvers allow post-ischemic accumulation of autacoids, which may trigger protection. Intermittent infusion of either bradykinin or diazoxide during early reperfusion triggered PostC protection via redox signaling. Here we tested whether intermittent adenosine (ADO) may trigger PostC-like cardioprotection. Isolated
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