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Merck
모든 사진(1)

주요 문서

95140

Sigma-Aldrich

Retinyl acetate

concentrate (~50% (w/w) in peanut oil), ~1500 U/mg

동의어(들):

Retinol acetate, Vitamin A acetate

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About This Item

실험식(Hill 표기법):
C22H32O2
CAS Number:
Molecular Weight:
328.49
Beilstein:
1915439
MDL number:
UNSPSC 코드:
12352200
eCl@ss:
34058009
PubChem Substance ID:
NACRES:
NA.79

생물학적 소스

synthetic

분석

~95% (HPLC)

형태

liquid

품질

concentrate (~50% (w/w) in peanut oil)

특이 활성도

~1500 U/mg

포함

DL-α-tocopherol as stabilizer

색상

yellow to very dark yellow

mp

57-58 °C

저장 온도

2-8°C

SMILES string

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

InChI key

QGNJRVVDBSJHIZ-QHLGVNSISA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Vitamin A is also known as retinol. Retinaldehyde, retinoic acid and retinyl esters are the derivatives of retinol. Retinol consists of a 20-carbon molecule. It also contains a cyclohexanyl ring with a side chain of four double bonds and an alcohol end group. Vitamin A is naturally present in the body as retinyl ester and β-carotene. Retinyl acetate, retinyl propionate and retinyl palmitate are analogs of retinol.

생화학적/생리학적 작용

Retinyl esters are stored in the liver and get converted to retinol before absorption by the intestine. Retinal plays a role in eye vision as it is a part of rhodopsin. Retinol binds to the retinol binding proteins in the plasma. Retinyl acetate has applications in cosmetology.

기타 정보

isomeric purity: ~95% all-trans- and ~5% 13-cis-isomer
Review: Systematic mode of action of vitamin A

주의사항

crystallized product can be liquidified by heating to 65°C

단위 정의

1 U corresponds to 1 international unit acc. to Ph Eur II, 217 (1983)

물리적 형태

may partially crystallize

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Chronic 4 - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Systemic mode of action of vitamin A.
J Ganguly et al.
Vitamins and hormones, 38, 1-54 (1980-01-01)
Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
Mukherjee S, et al.
Clinical Interventions in Aging, 1(4), 327-327 (2006)
Natalia Cernicchiaro et al.
Foodborne pathogens and disease, 7(9), 1071-1081 (2010-05-27)
Alteration of the gastro-intestinal tract through manipulation of cattle diets has been proposed as a preharvest control measure to reduce fecal shedding of Escherichia coli O157:H7. The objective of this study was to examine the effects of the energy source's
Tadao Maeda et al.
Investigative ophthalmology & visual science, 50(9), 4368-4378 (2009-05-02)
Mice lacking retinal pigment epithelium-specific 65-kDa protein (RPE65) develop retinopathy and blindness resembling Leber congenital amaurosis. Effects of 9-cis-retinyl acetate (9-cis-R-Ac) on visual function and retinopathy progression were tested in Rpe65(-/-) mice. Young C57Bl/6 mice were given 9-cis-R-Ac in each
Tadao Maeda et al.
Human molecular genetics, 18(12), 2277-2287 (2009-04-03)
Inactivating mutations in the retinoid isomerase (RPE65) or lecithin:retinol acyltransferase (LRAT) genes cause Leber congenital amaurosis (LCA), a severe visual impairment in humans. Both enzymes participate in the retinoid (visual) cycle, the enzymatic pathway that continuously generates 11-cis-retinal, the chromophore

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