콘텐츠로 건너뛰기
Merck
모든 사진(1)

Key Documents

363R-3

Sigma-Aldrich

PAX-8 (SP348) Rabbit Monoclonal Antibody

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12352203

생물학적 소스

rabbit blood

Quality Level

결합

unconjugated

항체 형태

IgG fraction of tissue culture supernatant

항체 생산 유형

primary antibodies

클론

SP348

설명

For In Vitro Diagnostic Use in Select Regions

형태

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL (concentrate (363R-34-RUO) Research Use Only)
vial of 0.1 mL
(concentrate (363R-34))

vial of 0.5 mL (concentrate (363R-35))
vial of 1.0 mL (concentrate (363R-36))
vial of 1.0 mL (concentrate (363R-36-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute (363R-37-RUO) Research Use Only)
vial of 1.0 mL (pre-dilute ready-to-use (363R-37))
vial of 25.0 mL (pre-dilute ready-to-use (363R-30))
vial of 25.0 mL (pre-dilute ready-to-use (363R-30-RUO))
vial of 7.0 mL (pre-dilute ready-to-use (363R-38))
vial of 7.0 mL (pre-dilute ready-to-use (363R-38-RUO) Research Use Only)

제조업체/상표

Cell Marque

기술

immunocytochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:10-1:20 (concentrated))

동형

IgG

제어

ovarian carcinoma, papillary carcinoma of thyroid, renal cell carcinoma, (Fallopian Tube)

배송 상태

wet ice

저장 온도

2-8°C

시각화

nuclear

일반 설명

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidney, and thyroid, with continued expression in neoplastic transformation of some epithelial cell types of these mature tissues.1 It can be useful for marking several types of carcinoma including, but not limited to, ovarian serous carcinoma, clear cell renal cell carcinoma and papillary thyroid carcinoma. Certain anti-PAX-8 antibodies may react with lymphocytes and their neoplasms, which has been attributed to cross-reactivity with PAX-5 due to sequence homology between PAX-8 and PAX-5, but clone SP348 does not exhibit reactivity in these cell types.

품질

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

제조 메모

Download the IFU specific to your product lot and format
Note: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

적합한 제품을 찾을 수 없으신가요?  

당사의 제품 선택기 도구.을(를) 시도해 보세요.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Lucas Moretti et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 25(2), 231-236 (2011-11-01)
Recently, reports using immunohistochemistry and a polyclonal antibody directed against the N-terminal region of PAX8 describe PAX8 expression in malignant lymphomas. As the N-terminal regions of PAX family members, including the B-cell transcription factor PAX5, have high sequence homology, we
Ayhan Ozcan et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 24(6), 751-764 (2011-02-15)
PAX 8 is a transcription factor that is essential for embryonic development of the kidney, Müllerian organs, and thyroid. It may also have a role in tumor development in these organs. The diagnostic utility of PAX 8 has not been
Guo-Xia Tong et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(9), 1218-1227 (2009-06-16)
Cell-lineage-specific transcription factors are a group of regulatory proteins expressed in embryonic, differentiated, or neoplastic cells of the same lineage and represent a valuable repertoire of tissue-specific markers for the diagnosis of human tumors. Together with PAX2, PAX8 is a
Daisuke Nonaka et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 21(2), 192-200 (2007-12-18)
Thyroid-specific transcription factors, Pax8, TTF-1, and TTF-2, are crucial for thyroid organogenesis and differentiation. Compared with TTF-1, the other two markers have scarcely been investigated in surgical pathology. The goal of this study is to evaluate the expressions of these
Daisuke Nonaka et al.
The American journal of surgical pathology, 32(10), 1566-1571 (2008-08-30)
The ovary is a common site of involvement for metastasis and the breast is one of the most common sources. Metastatic breast carcinoma can mimic a primary ovarian carcinoma. Pax8 is a crucial transcription factor for organogenesis of the thyroid

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.