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Merck
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문서

Y0000155

Tramadol hydrochloride

European Pharmacopoeia (EP) Reference Standard

동의어(들):

(±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride

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About This Item

실험식(Hill 표기법):
C16H25NO2 · HCl
CAS Number:
Molecular Weight:
299.84
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

tramadol

제조업체/상표

EDQM

약물 제어

USDEA Schedule IV

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C

InChI

1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1

InChI key

PPKXEPBICJTCRU-XMZRARIVSA-N

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일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Tramadol is a synthetic opiate agonist analgesic, widely used in patients suffering from moderate to severe chronic pain. It is considered safe when compared to other opioids. It contributes to the analgesic activity by blocking the nociceptive impulses at the spinal level, inhibiting the norepinephrine and serotonin reuptake.

애플리케이션

This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.

생화학적/생리학적 작용

Opioid analgesic; P450 substrate.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

기타 정보

Sales restrictions may apply.

픽토그램

Skull and crossbonesEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3

표적 기관

Central nervous system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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이미 열람한 고객

Slide 1 of 4

1 of 4

Analgesic oral efficacy of tramadol hydrochloride in postoperative pain
Sunshine A, et al.
Clinical Pharmacology and Therapeutics, 51(6), 740-746 (1992)
Kinetic spectrophotometric determination of tramadol hydrochloride in pharmaceutical formulation
Abdellatef EH
Journal of Pharmaceutical and Biomedical Analysis, 29(5), 835-842 (2002)
Application of HPLC for the simultaneous determination of aceclofenac, paracetamol and tramadol hydrochloride in pharmaceutical dosage form
Chandra P, et al.
Scientia Pharmaceutica, 80(2), 337-352 (2012)
The clinical use of tramadol hydrochloride
Bamigbade AT and Langford MR
Pain, 5(6), 155-182 (1998)
HPLC determination and validation of tramadol hydrochloride in capsules
Kartinasari FW, et al.
Journal of Liquid Chromatography and Related Technologies, 27(4), 737-744 (2004)

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