T7645

Tetracaine hydrochloride

Sigma Reference Standard

• 동의어(들): 4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester, Amethocaine hydrochloride
• 실험식(Hill 표기법): C₁₅H₂₄N₂O₂ · HCl
• CAS Number: 136-47-0
• Molecular Weight: 300.82
• MDL number: MFCD00038912
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329826873

속성

• Grade: Sigma Reference Standard
• 포장: vial of 250 mg
• solubility: alcohol: soluble in 40 parts solvent; chloroform: soluble in 30 parts of solvent; H₂O: soluble 50 mg/mL, clear, colorless; acetone: insoluble; benzene: insoluble; diethyl ether: insoluble
• SMILES string: Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
• InChI: 1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
• InChI key: PPWHTZKZQNXVAE-UHFFFAOYSA-N
• 유전자 정보: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

설명

애플리케이션

Tetracaine hydrochloride has been used to analyze Ca2+ release from sarcoplasmic reticulum (SR) in neonatal ventricular cardiomyocytes (NVCMs). Tetracaine hydrochloride has also been used as a component of protease digestion buffers.

Topical ophthalmic anesthetic; used for spinal anesthesia

생화학적/생리학적 작용

Blocks voltage-sensitive release of Ca²⁺ from sarcoplasmic reticulum.

포장

Supplied in amber screw-cap vials

제조 메모

Tetracaine hydrochloride dissolves in water at 50 mg/ml to yield a clear, colorless solution. It is also soluble in 40 parts alcohol and 30 parts chloroform. However, it is practically insoluble in ether benzene or acetone.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301,H319,H336
• 예방조치 성명서: P261 - P264 - P270 - P271 - P301 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
• 표적 기관: Central nervous system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable