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Merck
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문서

PHR1343

Supelco

Sulfadiazine

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Sulfadiazine, 4-Amino-N-(2-pyrimidinyl)benzenesulfonamide, N1-(Pyrimidin-2-yl)sulfanilamide

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About This Item

실험식(Hill 표기법):
C10H10N4O2S
CAS Number:
Molecular Weight:
250.28
Beilstein:
6733588
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to Ph. Eur. S1800000
traceable to USP 1625009

API family

sulfadiazine

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

mp

253 °C (dec.) (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-30°C

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ncccn2

InChI

1S/C10H10N4O2S/c11-8-2-4-9(5-3-8)17(15,16)14-10-12-6-1-7-13-10/h1-7H,11H2,(H,12,13,14)

InChI key

SEEPANYCNGTZFQ-UHFFFAOYSA-N

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일반 설명

Sulfadiazine is a bacteriostatic drug, that belongs to the class of medication referred as sulfonamide antibiotics. It is generally used in the treatment of cerebral meningitis, pneumonia, staphylococcal and streptococcal sepsis.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

애플리케이션

Sulfadiazine may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAC3953 in the slot below. This is an example certificate only and may not be the lot that you receive.

픽토그램

Health hazardExclamation markEnvironment

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2


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문서 라이브러리 방문

Development and validation of a stability-indicating HPLC method for the simultaneous determination of sulfadiazine sodium and trimethoprim in injectable solution formulation
Ghanem MM and Abu-Lafi SA
Scientia Pharmaceutica, 81(1), 167-182 (2013)
Sulfadiazine
European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
European pharmacopoeia, 3674-3675 (2017)
Simultaneous determination of enrofloxacin, silver sulfadiazine, hydrocortisone acetate, hydrocortisone sodium succinate, and preservative excipients in pharmaceutical preparations using HPLC-DAD method
Rosa AM, et al.
Chromatographia, 80(11), 1641-1649 (2017)
Determination of the content and the related substances of silver sulfadiazine gel by HPLC
Li Y, et al.
Chinese Journal of Hospital Pharmacy, 24(8), 474-474 (2004)
33 - Antimicrobial Drugs
Synthesis of Essential Drugs, 499-523 (2006)

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