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Merck
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문서

G4382

Supelco

(±)-Gossypol-acetic acid

analytical standard, crystalline complex consisting of equimolar quantities of gossypol and acetic acid, ~95%

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C30H30O8 · C2H4O2
CAS Number:
12542-36-8
Molecular Weight:
578.61
MDL number:
MFCD00058385
UNSPSC 코드:
41116107
PubChem Substance ID:
329799926
NACRES:
NA.24

Grade

analytical standard

분석

~95% (HPLC)
~95%

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

food and beverages

형식

neat

저장 온도

−20°C

SMILES string

CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c3c(C)cc4c(C(C)C)c(O)c(O)c(C=O)c4c3O

InChI

1S/C30H30O8.C2H4O2/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36;1-2(3)4/h7-12,33-38H,1-6H3;1H3,(H,3,4)

InChI key

NIOHNDKHQHVLKA-UHFFFAOYSA-N

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Reported to inhibit the autolytic conversion of pepsinogen to pepsin.

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Warning

유해 및 위험 성명서

H302,H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Choose from one of the most recent versions:

시험 성적서(COA)

Lot/Batch Number
0000342939
0000342940
0000196316
0000204909
0000204910

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Zhong Guo et al.
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The present study was conducted to investigate the effects of gossypol acetic acid (GAA) on the proliferation of human mucoepidermoid carcinoma cell line MEC-1 in vitro and its possible molecular mechanisms of DNA double-strand breaks (DSB). MTT assay was performed
Asli Kisim et al.
Journal of cancer research and clinical oncology, 138(7), 1155-1163 (2012-03-14)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and has been shown to induce extrinsic pathway of apoptosis in many types of cancer cells. AT-101, an (-)-enantiomer of gossypol, is a potent anticancer agent that
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