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Merck
모든 사진(1)

문서

92951

Supelco

Vasicine

analytical standard

동의어(들):

(−)-Peganine, (3S)-1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazolin-3-ol

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About This Item

실험식(Hill 표기법):
C11H12N2O
CAS Number:
Molecular Weight:
188.23
MDL number:
UNSPSC 코드:
85151701
PubChem Substance ID:

Grade

analytical standard

분석

≥95.0% (HPLC)

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

food and beverages

형식

neat

SMILES string

O[C@@H]1C2=NC3=CC=CC=C3CN2CC1

InChI

1S/C11H12N2O/c14-10-5-6-13-7-8-3-1-2-4-9(8)12-11(10)13/h1-4,10,14H,5-7H2/t10-/m0/s1

InChI key

YIICVSCAKJMMDJ-JTQLQIEISA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

B F Gibbs
International journal of immunopathology and pharmacology, 22(4), 919-927 (2010-01-16)
Ambroxol is a widely used secretolytic agent originally developed from vasicine, a natural alkaloid found in Adhatoda vasica, extracts of which have been used to treat bronchitis, asthma, and rheumatism. We previously reported that ambroxol inhibits IgE-dependent mediator secretion from
Pragya Misra et al.
The Journal of antimicrobial chemotherapy, 62(5), 998-1002 (2008-08-13)
The aim of this study was to resolve the putative pathway responsible for death induced by peganine hydrochloride dihydrate isolated from Peganum harmala seeds at cellular, structural and molecular level in Leishmania donovani, a causative agent of fatal visceral leishmaniasis.
Sergey V Shevyakov et al.
Natural product research, 20(8), 735-741 (2006-06-07)
A reliable and high-yielding procedure for preparation of 7-aryl and 7-heteroaryl derivatives of (+/-)-vasicine in two steps from the naturally occurring material is described. This protocol broadens the chemical space for selective modifications of the vasicine tricyclic structure, thereby making
Sergey V Shevyakov et al.
Natural product research, 20(9), 871-881 (2006-06-07)
A general procedure for direct lithiation of deoxyvasicine was developed. 3-Lithiodeoxyvasicine intermediate was found to react with various aliphatic ketones providing derivatives of 3-(hydroxyalkyl)deoxyvasicine in good yields. Similar reaction with 4-alkylcyclohexanones yielded respective trans-adducts exclusively. This novel protocol was successfully
Tejas Vyas et al.
Fitoterapia, 82(3), 446-453 (2010-12-29)
The oral bioavailability of vasicine (1) was investigated in hard gelatin capsules of lyophilized Vasa Swaras (aqueous extract of Adhatoda vasica Nees.,Fam.: Acanthaceae) The rat pharmacokinetic profile of lyophilized Vasa Swaras, Vasa Swaras, vasicine (1) (chief marker compounds of A.

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