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Merck
모든 사진(1)

문서

91801

Supelco

Cynarin

analytical standard

동의어(들):

1,3-Dicaffeoylquinic acid, (1R,3R,4S,5R)-1,3-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxycyclohexanecarboxylic acid, 1,5-DQA, 1,5-Dicaffeoylquinic acid, Cynarin, Cynarine

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About This Item

실험식(Hill 표기법):
C25H24O12
CAS Number:
Molecular Weight:
516.45
MDL number:
UNSPSC 코드:
85151701
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

분석

≥98.0% (HPLC)

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

불순물

≤10.0% water

응용 분야

food and beverages

형식

neat

저장 온도

2-8°C

SMILES string

O[C@@H]1C[C@](C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H]1O)(OC(=O)\C=C\c3ccc(O)c(O)c3)C(O)=O

InChI

1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(24(34)35,11-19(30)23(20)33)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,33H,11-12H2,(H,34,35)/b7-3+,8-4+/t19-,20-,23+,25-/m1/s1

InChI key

YDDUMTOHNYZQPO-RVXRWRFUSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Cynarin is an active constituent of artichoke plant, exhibiting choleretic and hypocholesterolemic activities. It is also widely used in phytoterapic preparations with special indication in hepatic affections.

애플리케이션

Cynarin may be used as an analytical reference standard for the quantification of the analyte in plasma samples using high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Phenolic compound found in artichoke. Antioxidant and choleretic properties. Potential immunosuppressive agent.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

기타 정보

This compound is commonly found in plants of the genus: arnica echinacea

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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Lot/Batch Number

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문서 라이브러리 방문

Validated HPLC method for cynarin determination in biological samples
Alonso RM, et al.
Acta Acad. Med. Sin., 25(2), 267-267 (2006)
Guo-Chung Dong et al.
Journal of medicinal chemistry, 49(6), 1845-1854 (2006-03-17)
AFTIR (after flowing through immobilized receptor) is a novel method for screening herbal extracts for pharmaceutical properties. Using AFTIR, we identified Cynarin in Echinacea purpurea by its selective binding to chip immobilized CD28, a receptor of T-cells, which is instrumental
Esra Erikel et al.
Journal of ethnopharmacology, 237, 171-181 (2019-03-21)
Cynarin is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging and antioxidant activity. The origin of artichoke species appears to be Mediterranean region. Two of these species, globe artichoke (Cynara cardunculus var. scolymus L.) and
Yi Wang et al.
Bioorganic & medicinal chemistry letters, 21(23), 7064-7067 (2011-10-22)
The complex and highly impermeable cell wall of Mycobacterium tuberculosis (Mtb) is largely responsible for the ability of the mycobacterium to resist the action of chemical therapeutics. An L-rhamnosyl residue, which occupies an important anchoring position in the Mtb cell
Bianca Sperl et al.
Bioorganic & medicinal chemistry letters, 19(12), 3305-3309 (2009-05-12)
In this Letter, we report the natural products salvianolic acid A, salvianolic acid B, and caftaric acid as inhibitors of the protein-protein interactions mediated by the SH2 domains of the Src-family kinases Src and Lck, two established disease targets. Moreover

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