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Merck
모든 사진(1)

문서

37019

Supelco

Atropine

analytical standard

동의어(들):

Hyoscyamine, Tropine tropate, endo-(±)-α-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester

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About This Item

실험식(Hill 표기법):
C17H23NO3
CAS Number:
Molecular Weight:
289.37
Beilstein:
91260
EC Number:
MDL number:
UNSPSC 코드:
85151701
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

cleaning products
cosmetics
food and beverages
personal care

형식

neat

저장 온도

−20°C

SMILES string

CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3/t13-,14+,15+,16?

InChI key

RKUNBYITZUJHSG-SPUOUPEWSA-N

유전자 정보

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일반 설명

Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
Atropine is an antimuscarinic drug, which is classified under the tropane alkaloid family of compounds.
For the analysis of the phytotoxins.

애플리케이션

Atropine may be used as a reference standard for the determination of atropine in:
  • Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
  • Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
  • Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
  • Plant materials by liquid-liquid extraction and EXtrelut® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Atropine may be used as a reference standard for the determination of atropine in:
  • Blood samples by liquid chromatography combined with electrospray ionization-triple quadrupole mass spectrometry (LC-ESI-MS/MS).
  • Hair samples by ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC-HRMS) consisting of single-stage Orbitrap MS system with ESI interface.
  • Oganic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
  • Plant materials by liquid-liquid extraction and EXtrelut® column clean-up followed by analysis using gas chromatography (GC) coupled with flame ionization detector (FID) and MS.

생화학적/생리학적 작용

Competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors.

재구성

Dried down, ~100μg/mL after reconstitution with 1 mL of water

분석 메모

purity : ≥96.0% (HPLC)

법적 정보

Extrelut is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

이미 열람한 고객

Are tropane alkaloids present in organic foods? Detection of scopolamine and atropine in organic buckwheat (Fagopyron esculentum L.) products by UHPLC-MS/MS.
<BIG>Cirlini M, et al.</BIG>
Food Chemistry, 239, 141-147 (2018)
High-throughput screening for drugs of abuse and pharmaceutical drugs in hair by liquid-chromatography-high resolution mass spectrometry (LC-HRMS).
<BIG>Odoardi S, et al.</BIG>
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 133, 302-310 (2017)
Enantiomeric determination and evaluation of the racemization process of atropine in Solanaceae seeds and contaminated samples by high performance liquid chromatography-tandem mass spectrometry.
<BIG>Marin-Saez J, et al.</BIG>
Journal of Chromatography A, 1474, 79-84 (2016)
Isolation of atropine and scopolamine from plant material using liquid-liquid extraction and EXtrelut columns
<BIG>Sramska P, et al.</BIG>
Journal of Chromatography. B, Biomedical Sciences and Applications, 1043, 202-208 (2017)
Method validation for simultaneous determination of atropine, pralidoxime and 12 organophosphorus compounds in blood samples by means of high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
<BIG>Marques GLM, et al</BIG>.
Journal of Chromatography. B, Biomedical Sciences and Applications, 1097, 44-53 (2018)

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