추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
liquid
미포함
preservative
종 반응성
human, mouse
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
avoid repeated freeze/thaw cycles
동형
IgG
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... MSH2(4436)
일반 설명
Purified rabbit polyclonal antibody. Recognizes the ~100 kDa MSH2 protein.
Recognizes the ~100 kDa MSH2 protein in HCT116 and SW480 cells and in colon tissue.
This Anti-MSH2 (Ab-3) Rabbit pAb is validated for use in Frozen Sections, Immunoblotting, Immunoprecipitation, Paraffin Sections for the detection of MSH2 (Ab-3).
면역원
full length, recombinant, human MSH2
애플리케이션
Frozen Sections (2 µg/ml)
Immunoblotting (1 µg/ml, chemiluminescence)
Immunoprecipitation (1 µg/sample)
Paraffin Sections (see application references)
Immunoblotting (1 µg/ml, chemiluminescence)
Immunoprecipitation (1 µg/sample)
Paraffin Sections (see application references)
포장
Please refer to vial label for lot-specific concentration.
경고
Toxicity: Standard Handling (A)
기타 정보
Bronner, C.E., et al. 1994. Nature368, 258.
Papadopoulos, N., et al. Science263, 1625.
Peltomäki, P.T. 1994. Ann. Medicine26, 215.
Fishel, R., et al. 1993. Cell75, 1027.
Leach, F.S., et al. 1993. Cell75, 1215.
Lindbolm, A., et al. 1993. Nat. Genet.5, 279.
Papadopoulos, N., et al. Science263, 1625.
Peltomäki, P.T. 1994. Ann. Medicine26, 215.
Fishel, R., et al. 1993. Cell75, 1027.
Leach, F.S., et al. 1993. Cell75, 1215.
Lindbolm, A., et al. 1993. Nat. Genet.5, 279.
법적 정보
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
J Barwell et al.
Journal of medical genetics, 44(8), 516-520 (2007-05-08)
Reports of differential mutagen sensitivity conferred by a defect in the mismatch repair (MMR) pathway are inconsistent in their conclusions. Previous studies have investigated cells established from immortalised human colorectal tumour lines or cells from animal models. We examined primary
Jennifer A McKinney et al.
Nature communications, 11(1), 236-236 (2020-01-15)
Alternative DNA structure-forming sequences can stimulate mutagenesis and are enriched at mutation hotspots in human cancer genomes, implicating them in disease etiology. However, the mechanisms involved are not well characterized. Here, we discover that Z-DNA is mutagenic in yeast as
Jennifer L Cyr et al.
Molecular carcinogenesis, 51(8), 647-658 (2011-08-13)
Lynch syndrome (LS) is caused by germline mutations in DNA mismatch repair (MMR) genes. MMR recognizes and repairs DNA mismatches and small insertion/deletion loops. Carriers of MMR gene variants have a high risk of developing colorectal, endometrial, ovarian, and other
Samar Hassen et al.
Journal of experimental & clinical cancer research : CR, 30, 100-100 (2011-10-25)
A broad population-based assay to detect individuals with Lynch Syndrome (LS) before they develop cancer would save lives and healthcare dollars via cancer prevention. LS is caused by a germline mutation in a DNA mismatch repair (MMR) gene, especially protein
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