MABN92-AF488

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate

clone 20A12.1, from mouse, ALEXA FLUOR^™ 488

• 동의어(들): Allograft inflammatory factor 1, AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: ALEXA FLUOR^™ 488
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: 20A12.1, monoclonal
• 종 반응성: human, mouse, rat
• 기술: immunohistochemistry: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_001614
• UniProt 수납 번호: P55008
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... AIF1(199)

설명

일반 설명

Allograft inflammatory factor 1 (UniProt P55008; also known as AIF-1, Daintain, Interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, Protein G1) is encoded by the AIF1 (also known as G1, IBA1) gene (Gene ID 199) in human. Iba1/AIF1 is a 17 kDa interferon-gamma- (IFN-gamma-) inducible, Ca(2+)-binding EF-hand protein. Iba1/AIF1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma. It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and macrophage activation/function. It is also shown to be expressed in microglial cells in autominnume disesase models such as experimental autoimmune encephalomyelitis, neuritis and uveitis.

애플리케이션

Anti-Iba1/AIF1 Antibody, clone 20A12.1, Alexa Fluor^™ 488 Conjugate is an antibody against Iba1/AIF1 for use in Immunohistochemistry.

품질

Evaluated by Immunohistochemistry in human spleen tissue.

Immunohistochemistry Analysis: A 1:300 dilution of this antibody detected Iba1/AIF1 in human spleen tissue.

표적 설명

~17 kDa observed

기타 정보

Concentration: Please refer to lot specific datasheet.

법적 정보

ALEXA FLUOR is a trademark of Life Technologies

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable