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Merck
모든 사진(2)

Key Documents

MABN250

Sigma-Aldrich

Anti-RA-induced protein 17 Antibody, clone 5H5.1

clone 5H5.1, from mouse

동의어(들):

Retinoic acid-induced protein 17, ZMIZ1, Zinc finger MIZ domain-containing protein 1, PIAS-like protein Zimp10

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

5H5.1, monoclonal

종 반응성

human

기술

immunohistochemistry: suitable
western blot: suitable

동형

IgG1κ

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... ZMIZ1(57178)

일반 설명

Retinoic acid-induced protein 17 (RAI17) is also called Zinc finger MIZ domain-containing protein 1 (ZMIZ1), and PIAS-like protein Zimp10. Retinoic acid-induced protein 17 promotes AR sumoylation and increases AR ligand-dependent transcriptional activity. Retinoic acid-induced protein 17 is highly expressed in ovary and at lower levels in prostate, spleen and testis.

면역원

Recombinant protein corresponding to human RA-induced protein 17.

애플리케이션

Detect Retinoic acid-induced protein 17 using this mouse monoclonal antibody, Anti-RA-induced protein 17 Antibody, clone 5H5.1 validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected RA-induced protein 17 in human thalamus tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

품질

Evaluated by Western Blotting in SH-SY5Y cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected RA-induced protein 17 in 10 µg of SH-SY5Y cell lysate.

표적 설명

~115 kDa observed. Uniprot describes 2 isoforms produced by alternative splicing at ~115 kDa and ~107 kDa

물리적 형태

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Sameer Aryal et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(18) (2021-04-29)
Loss of the fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS). FMRP is widely thought to repress protein synthesis, but its translational targets and modes of control remain in dispute. We previously showed that genetic removal of

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