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Merck
모든 사진(1)

문서

MABN160

Sigma-Aldrich

Anti-Syntenin-1 Antibody, clone 4F4.1

clone 4F4.1, 1 mg/mL, from mouse

동의어(들):

Syntenin-1, Melanoma differentiation-associated protein 9, MDA-9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, TACIP18, Scaffold protein Pbp1, Syndecan-binding protein 1

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

4F4.1, monoclonal

종 반응성

human

농도

1 mg/mL

기술

western blot: suitable

동형

IgG1κ

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... SDCBP(6386)

일반 설명

The syndecans are transmembrane proteoglycans that place structurally heterogeneous heparan sulfate chains at the cell surface and a highly conserved polypeptide in the cytoplasm. Syntenin (also known as SDCBP) is an approximately 33 kDa scaffolding protein that that binds to kainate receptor subunits via a PDZ interaction. There is extensive colocalization of syntenin and kainate receptors with particularly intense labeling for both proteins at growth cones. It is proposed that syntenin has a role both in controlling membrane organization and in determining the formation and maturation of synapses.

면역원

GST-tagged recombinant protein corresponding to human Syntenin-1. The immunogen has a 98% homology to Mouse and Rat.

애플리케이션

Detect Syntenin-1 using this Anti-Syntenin-1 Antibody, clone 4F4.1 validated for use in western blotting.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

품질

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Syntenin-1 in 10 µg of HEK293 cell lysate.

표적 설명

~32 kDa observed

물리적 형태

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Diantha Van De Vlekkert et al.
Bio-protocol, 10(7), e3576-e3576 (2021-03-05)
Exosomes are dynamic nanovesicles secreted by virtually all cells and are present in all biological fluids. Given their highly heterogeneous content exosomes have been implicated in many physiological and pathological processes that they exert by influencing cell-cell and cell-ECM communication.

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