MAB5354
Anti-Amyloid Precursor Protein (APP) Antibody
CHEMICON®, mouse monoclonal, 4.1
동의어(들):
Anti-AAA, Anti-ABETA, Anti-ABPP, Anti-AD1, Anti-APPI, Anti-CTFgamma, Anti-CVAP, Anti-PN-II, Anti-PN2, Anti-alpha-sAPP, Anti-preA4
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모든 사진(1)
About This Item
UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
추천 제품
제품명
Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1, clone 4.1, Chemicon®, from mouse
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
4.1, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... APP(351)
특이성
Amyloid-beta Precursor Protein, KPI (Kunitz protease inhibitor) domain. The antibody reacts with both native and recombinant protein. The antibody has been shown to partially inhibit protease inhibitory properties.
면역원
Epitope: KPI domain
Purified recombinant KPI domain of Amyloid-beta precursor protein.
애플리케이션
Anti-Amyloid β Precursor Protein Antibody, KPI domain, clone 4.1 detects level of Amyloid β Precursor Protein & has been published & validated for use in ELISA, WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Western blot: 2-5 μg/mL using ECL on human brain or platelets. Recognizes a protein of 100-120 kDa.
Immunohistochemistry: 2-5 μg/mL on frozen tissue sections.
ELISA: 1 μg/mL in a direct assay and 10 μg/mL in an indirect assay.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 2-5 μg/mL on frozen tissue sections.
ELISA: 1 μg/mL in a direct assay and 10 μg/mL in an indirect assay.
Optimal working dilutions must be determined by the end user.
물리적 형태
Format: Purified
Purified immunoglobulin. Liquid in 20 mM Sodium phosphate buffer with 150 mM NaCl.
저장 및 안정성
Maintain at 2-8°C in undiluted aliquots for up to 6 months of date of receipt.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Jochen Winterer et al.
Cell reports, 19(6), 1110-1116 (2017-05-13)
The distinctive firing pattern of grid cells in the medial entorhinal cortex (MEC) supports its role in the representation of space. It is widely believed that the hexagonal firing field of grid cells emerges from neural dynamics that depend on
Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-? production.
Bordji, K; Becerril-Ortega, J; Nicole, O; Buisson, A
The Journal of Neuroscience null
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