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Merck
모든 사진(1)

문서

MAB356

Sigma-Aldrich

Anti-Substance P Antibody, pain, clone NC1

culture supernatant, clone NC1, Chemicon®

동의어(들):

Anti-Hs.2563, Anti-NK2, Anti-NKNA, Anti-NPK, Anti-TAC2

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rat

Quality Level

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

NC1, monoclonal

종 반응성

human

종 반응성(상동성에 의해 예측)

mammals

제조업체/상표

Chemicon®

기술

immunohistochemistry: suitable

동형

IgG2a

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... TAC1(6863)

특이성

Reacts with COOH-terminal end of Substance P. No cross-reactivity to Leu- or Met- enkephalin, somatostatin or beta-endorphin. Eledoisin 5%.

면역원

Substance P conjugated to BSA.

애플리케이션

1:100 - 1:200 by immunohistochemistry on human brain.

Optimal working dilutions must be determined by end user.
Detect Substance P using this Anti-Substance P Antibody, pain, clone NC1 validated for use in IH.

물리적 형태

Lyophilized Supernatant, preservative free.

저장 및 안정성

Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2


시험 성적서(COA)

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문서 라이브러리 방문

Liang Han et al.
Nature neuroscience, 21(3), 324-328 (2018-02-07)
Asthma, accompanied by lung inflammation, bronchoconstriction and airway hyper-responsiveness, is a significant public health burden. Here we report that Mas-related G protein-coupled receptors (Mrgprs) are expressed in a subset of vagal sensory neurons innervating the airway and mediates cholinergic bronchoconstriction
High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse.
Ding, S; Chi, MM; Scull, BP; Rigby, R; Schwerbrock, NM; Magness, S; Jobin, C; Lund, PK
Testing null
Andrew P Ray et al.
Pharmacology, biochemistry, and behavior, 94(1), 211-218 (2009-08-25)
Research on the mechanisms of emesis has implicated multiple neurotransmitters via both central (dorsal vagal complex) and peripheral (enteric neurons and enterochromaffin cells) anatomical substrates. Taking advantage of advances in receptor-specific agonists, and utilizing Fos expression as a functional activity
Tibor Z Veres et al.
American journal of respiratory cell and molecular biology, 37(5), 553-561 (2007-06-30)
Neuroimmune interactions play a critical role in the pathogenesis of asthma. Symptoms like wheezing and cough have been attributed to neural dysregulation, whereas sensitization and the induction of allergic inflammation have been linked with the activity of dendritic cells. Neuropeptides
Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene.
Zimmer, A; Zimmer, AM; Baffi, J; Usdin, T; Reynolds, K; Konig, M; Palkovits, M; Mezey, E
Proceedings of the National Academy of Sciences of the USA null

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