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Merck
모든 사진(1)

문서

MAB3414

Sigma-Aldrich

Anti-Cytokeratin 8 Antibody, clone 4.1.18

clone 4.1.18, Chemicon®, from mouse

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

4.1.18, monoclonal

종 반응성

human

제조업체/상표

Chemicon®

기술

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

동형

IgG1

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... KRT8(3856)

특이성

The antibody reacts with human cytokeratin 8. There is no cross reactivity with human cytokeratin No. 7, 17, 18, or 19. Anti-cytokeratin No. 8 decorates single epithelia in stomach, colon, and small intestine, gall bladder, liver (bile ducts and hepatocytes) as well as pancreatic ducts and mammary gland ducts.

면역원

Cytoskeletal preparation of MCF-7 cells.

애플리케이션

This Anti-Cytokeratin 8 Antibody, clone 4.1.18 is validated for use in WB, IC, IH, IH(P) for the detection of Cytokeratin 8.
Western blot Immunocytochemistry Immunohistochemistry: Frozen sections, acetone fixed (5-10 μg/mL)

Paraffin sections, after trypsin treatment (5-20 μg/mL)

Optimal-working dilutions must be determined by end user.

결합

Replaces: 04-588

물리적 형태

Format: Purified
Lyophilized from 0.02 M Phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% sodium azide.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Cristián Vela Hinojosa et al.
PloS one, 8(9), e75062-e75062 (2013-10-03)
The mammary gland has long drawn the attention of the scientific community due to the limited knowledge of some fundamental aspects involved in the control of its function. Myotis velifer, a microchiropteran species, provides an interesting model to study some
Stanislava Merjava et al.
Investigative ophthalmology & visual science, 52(2), 787-794 (2010-10-12)
The purpose of this study was to investigate the expression of cytokeratin (CK) 8 in the corneoconjunctival epithelium. In 17 cadaveric corneoscleral discs and 3 other discs, the presence of CK8 alone or CK8, together with CK3, CK15, vimentin, and
Miranda Batchelor et al.
EMBO reports, 5(1), 104-110 (2004-01-08)
While remaining extracellular, enteropathogenic Escherichia coli (EPEC) establish direct links with the cytoskeleton of the target epithelial cell leading to the formation of actin-rich pedestals underneath attached bacteria. The translocated adaptor protein Tir forms the transmembrane bridge between the cytoskeleton
Leandi Krüger et al.
American journal of physiology. Gastrointestinal and liver physiology, 313(3), G180-G191 (2017-06-03)
Esophageal injury is a risk factor for diseases such as Barrett's esophagus (BE) and esophageal adenocarcinoma. To improve understanding of signaling pathways associated with both normal and abnormal repair, animal models are needed. Traditional rodent models of esophageal repair are
Sinyoung Kim et al.
International journal of molecular medicine, 27(5), 701-706 (2011-02-25)
Although recent studies have demonstrated the in vitro hepatic differentiation potential of mesenchymal stem cells (MSCs), the evidence supporting the in vivo engraftment of MSCs, hepatic differentiation and improvement of hepatic function is still lacking. We investigated in vivo hepatic

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