생물학적 소스
mouse
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
54B3, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
일반 설명
Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated alpha and beta subunits. More than 18 alpha and 8 beta subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits alpha 3 and alpha 6, two cytoplasmic variants, A and B, have been identified.
MAB2291 is a mouse monoclonal generated to a synthetic peptide in the cytoplasmic domain of integrin alpha 3B.
특이성
Anti-Integrin alpha 3B recognizes the cytoplasmic domain of integrin alpha 3B. Integrin alpha 3B is present in the microvascular structures in brain and heart.
SPECIES REACTIVITIES:
Although untested, a broad species reactivity is expected due to the conserved nature of the epitope.
SPECIES REACTIVITIES:
Although untested, a broad species reactivity is expected due to the conserved nature of the epitope.
면역원
Epitope: cytoplasmic domain
Synthetic peptide: CTRYYQIMPKYHAVRIREEERYPPPGSTLPTKK
애플리케이션
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
This Anti-Integrin α3 Antibody, cytoplasmic domain, clone 54B3 is validated for use in WB, IC, IH for the detection of Integrin α3.
Western Blotting
Immunocytochemistry
Immunohistochemistry
Optimal working dilutions must be determined by the end user.
Immunocytochemistry
Immunohistochemistry
Optimal working dilutions must be determined by the end user.
물리적 형태
Format: Purified
Purified. Liquid in PBS containing 0.1% sodium azide.
저장 및 안정성
Store at 2-8°C, or in small aliquots at -20°C.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.