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Merck
모든 사진(1)

문서

GF335

Sigma-Aldrich

IL-3,
Human Recombinant Animal Free

동의어(들):

Interleukin-3, IL3

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About This Item

UNSPSC 코드:
12352202
eCl@ss:
32160405
NACRES:
NA.77

불순물

<0.1 μg/mg protein endotoxin (<1 EU/μg)

Quality Level

UniProt 수납 번호

배송 상태

dry ice

일반 설명

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine.
Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
Product Source: Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.

애플리케이션

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

품질

Determined by its ability to stimulate the proliferation of human TF-1 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.

물리적 형태

Product is presented without additives and is filtered through a 0.2 micron filter before lyophilization.

저장 및 안정성

Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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