FCMAB180F

Milli-Mark^® Anti-CD13-FITC Antibody, clone WM-47

clone WM-47, Milli-Mark^®, from mouse

• 동의어(들): Aminopeptidase N (AP-N), hAPN, Alanyl aminopeptidase, Microsomal aminopeptidase, Aminopeptidase M (AP-M), gp150, Myeloid plasma membrane glycoprotein CD13
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: FITC conjugate
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: WM-47, monoclonal
• 종 반응성: human
• 제조업체/상표: Milli-Mark^®
• 기술: flow cytometry: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_001141.2
• UniProt 수납 번호: P15144
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ANPEP(290)

설명

일반 설명

CD13 is a 150 kDa Type II integral membrane protein composed of 967 amino acids (Turni, 2002; Ashmun, 1995; Look, 1989). CD13 is identical in structure to aminopeptidase N, a membrane-bound zinc-binding metalloprotease (Turni, 2002). CD13 is expressed on the surface of committed granulocyte-monocyte progenitors (CFU-GM) and by cells of the granulocyte and monocyte lineages at all stages of differentiation (Turni, 2002; Ashmun, 1995; Look, 1989). The antigen is also expressed on a small proportion of large granular lymphocytes, but not on B or T cells (Ashmun, 1995; Look, 1989). Further, CD13 is expressed on some non-hematopoietic cells including fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining the bile duct canaliculi (Turni, 2002; Ashmun, 1995; Look, 1989).
Anti-CD13, WM-47, was included in the Fourth and Fifth International Workshop and Conference on Leucocyte Differentiation Antigens and studies by a number of laboratories confirmed its reactivity with CD 13 (Ashmun, 1995; Look, 1989).

특이성

Antibody recognizes Human CD13 antigen.

면역원

Leukaemic cells from a case of chronic myeloid leukaemia (CML).

애플리케이션

Detect CD13 using this Milli-Mark Anti-CD13-FITC Antibody, clone WM-47 validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

품질

Evaluated by flow cytometry using human PBMCs

표적 설명

150 kDa (Turni, 2002; Ashmun, 1995; Look, 1989)

물리적 형태

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

저장 및 안정성

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

분석 메모

Control
PBMCs

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable