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Merck
모든 사진(1)

문서

EZHGIP

Millipore

Human GIP ELISA Kit

measures and quantify total GIP levels in 20 μL serum, plasma or cell culture samples

동의어(들):

Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Incretin hormone

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About This Item

UNSPSC 코드:
12161503
eCl@ss:
32161000
NACRES:
NA.32

product name

Human GIP (total) ELISA, This Human GIP (total) ELISA is used to measure & quantify GIP levels in Metabolism & Endocrine research.

Quality Level

종 반응성

human

포장

kit of 1 × 96 wells

파라미터

20 μL sample volume (4hr assay)

assay range

accuracy: 86.7%
linearity: 99.9%
sensitivity: 8.2 pg/mL
standard curve range: 8.2-2000 pg/mL

기술

ELISA: suitable

입력

sample type cell culture supernatant
sample type serum
sample type plasma (K2 EDTA)

NCBI 수납 번호

UniProt 수납 번호

응용 분야

research use

검출 방법

colorimetric (450nm/590nm)

배송 상태

wet ice

저장 온도

2-8°C

유전자 정보

human ... GNAI2(2771)

일반 설명

GIP, also known as a gastric inhibitory polypeptide, or glucose-dependent insulinotropic polypeptide is encoded by the gene mapped to human chromosome 17q12-q21. It is synthesized in and secreted from K cells in the intestinal epithelium. GIP secretion from the gastrointestinal tract plays a major role in glucose homeostasis. It stimulates insulin secretion from pancreatic β cells after oral ingestion of nutrients. In addition, GIP also promotes insulin biosynthesis, and β-cell proliferation and alleviates beta-cell apoptosis GIP also aids in fat metabolism by stimulating triglyceride synthesis in adipocytes. Elevated levels of GIP may lead to obesity and hyperinsulinemia. This Human GIP (total) ELISA is used to measure & quantify GIP levels in Metabolism & Endocrine research.

애플리케이션

Human GIP (total) ELISA has been used to measure total glucose-dependent insulinotropic polypeptide (GIP) in blood samples.

기타 정보

Research Sub Category Obesity Metabolic Disorders Room temperature, 3.5 hour assay, 20 µL sample volume, serum, plasma, or tissue culture medium Research Category Metabolism

면책조항

For research use only. Not for use in diagnostic procedures.

픽토그램

Skull and crossbonesCorrosionEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

L A Anderson et al.
Genomics, 17(3), 618-623 (1993-09-01)
To facilitate the positional cloning of the breast-ovarian cancer gene BRCA1, we constructed a high-density genetic map of the 8.3-cM interval between D17S250 and GIP on chromosome 17q12-q21. Markers were mapped by linkage in the CEPH and in extended kindreds
Colesevelam improves oral but not intravenous glucose tolerance by a mechanism independent of insulin sensitivity and ?-cell function.
Anna L Marina,Kristina M Utzschneider,Lorena A Wright,Brenda K Montgomery et al.
Diabetes Care null
Tsuyoshi Yanagimachi et al.
Molecular metabolism, 6(2), 226-231 (2017-02-10)
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) possess multiple bioactive isoforms that are rendered non-insulinotropic by the enzyme dipeptidyl peptidase-4 (DPP-4). Recently, some ELISA kits have been developed to specifically measure "active" GIP and GLP-1, but it is unclear
Dietary sugars stimulate fatty acid synthesis in adults.
Elizabeth J Parks, Lauren E Skokan, Maureen T Timlin, Carlus S Dingfelder
The Journal of Nutrition null
Frank Isken et al.
American journal of physiology. Endocrinology and metabolism, 295(2), E350-E355 (2008-05-29)
Menopause and premature gonadal steroid deficiency are associated with increases in fat mass and body weight. Ovariectomized (OVX) mice also show reduced locomotor activity. Glucose-dependent-insulinotropic-polypeptide (GIP) is known to play an important role both in fat metabolism and locomotor activity.

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