생물학적 소스
mouse
Quality Level
항체 생산 유형
primary antibodies
클론
10H11.E12, monoclonal
양식
liquid
포함
≤0.1% sodium azide as preservative
종 반응성
human, mouse
제조업체/상표
Calbiochem®
저장 조건
OK to freeze
avoid repeated freeze/thaw cycles
동형
IgG1
배송 상태
wet ice
저장 온도
−20°C
일반 설명
Protein G purified mouse monoclonal antibody. Recognizes the ~370 kDa ATM protein phosphorylated at Ser1981.
Recognizes the ~370 kDa ATM protein phosphorylated on Ser1981 in camptothecin-treated HeLa cells. Sold under license of U.S. Patent 7,108,992.
This PhosphoDetect Anti-ATM (pSer¹⁹⁸¹) Mouse mAb (10H11.E12) is validated for use in Immunoblotting, Immunocytochemistry for the detection of ATM (pSer¹⁹⁸¹).
면역원
Human
a synthetic phosphopeptide (SLAFEEGpSQSTTISS) corresponding to amino acids 1974-1988 surrounding the Ser¹⁹⁸¹ phosphorylation site of human ATM
애플리케이션
Immunoblotting (0.5 g/ml)
Immunocytochemistry (1.5 g/ml)
포장
Please refer to vial label for lot-specific concentration.
경고
Toxicity: Irritant (B)
물리적 형태
In PBS.
재구성
Following initial thaw, aliquot and freeze (-20°C).
분석 메모
Positive Control
HeLa cells treated with camptothecin (Cat. No. 208925)
HeLa cells treated with camptothecin (Cat. No. 208925)
기타 정보
Does not detect the unphosphorylated protein. Use 5% milk in TBS-T for blocking; the use of BSA is not recommended. The use of PBS-T is not recommended, as phosphate-containing buffers can contribute to high background with phosphospecific antibodies. Antibody should be titrated for optimal results in individual systems.
Horejsi, Z., et al. 2004. Oncogene23, 3122.
Abraham, R.T. 2003. Genes Dev.15, 2177.
Bakkenist, C.J. and Kastan, M.B. 2003. Nature421, 499.
Shiloh, Y. 2003. Nat. Rev. Cancer3, 155.
Abraham, R.T. 2003. Genes Dev.15, 2177.
Bakkenist, C.J. and Kastan, M.B. 2003. Nature421, 499.
Shiloh, Y. 2003. Nat. Rev. Cancer3, 155.
법적 정보
Sold under license of U.S. Patent 7,108,992.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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